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ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1)

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Sodium pump subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; Sodium/potassium-transporting ATPase subunit alpha-1

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1)
CCC G369
HGNC 799
MGI 88105
PubMed 23416519
RGD 2167
UniProt P05023
Wiki ATP1a1
ATP1a1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle.
This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG369Mi01 Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Positive Control; Immunogen; SDS-PAGE; WB.
RPG369Hu01 Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG369Mi01 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
PAG369Hu01 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
CAG369Hu22 Anti-ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody Loading Control of WB
CAG369Hu01 Anti-ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody Loading Control of WB.
MAG369Hu21 Monoclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
MAG369Hu22 Monoclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
MAG369Hu23 Monoclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
Assay Kits SEG369Mi ELISA Kit for ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG369Mi01 Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG369Mi01 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
Assay Kits SEG369Mi ELISA Kit for ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG369Mi01 Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG369Mi01 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
Assay Kits SEG369Mi ELISA Kit for ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG369Rb01 Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG369Rb51 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
PAG369Rb52 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
PAG369Rb01 Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) WB; IHC; ICC; IP.
Assay Kits SEG369Rb ELISA Kit for ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody Customized Service Offer
Assay Kits SEG369Mi ELISA Kit for ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Primary structure of the alpha-subunit of human Na,K-ATPase deduced from cDNA sequence."J. Biochem. 100:389-397(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization and quantification of full-length and truncated Na,K-ATPase alpha 1 and beta 1 RNA transcripts expressed in human retinal pigment epithelium."Gene 155:179-184(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The human Na, K-ATPase alpha 1 gene: characterization of the 5'-flanking region and identification of a restriction fragment length polymorphism."Genomics 6:451-460(1990) [PubMed] [Europe PMC] [Abstract]
  7. "Multiple genes encode the human Na+,K+-ATPase catalytic subunit."Proc. Natl. Acad. Sci. U.S.A. 84:4039-4043(1987) [PubMed] [Europe PMC] [Abstract]
  8. "Human placental Na+,K+-ATPase alpha subunit: cDNA cloning, tissue expression, DNA polymorphism, and chromosomal localization."Proc. Natl. Acad. Sci. U.S.A. 84:7901-7905(1987) [PubMed] [Europe PMC] [Abstract]
  9. "Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size."Nature 358:764-768(1992) [PubMed] [Europe PMC] [Abstract]
  10. "The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit."FEBS Lett. 217:275-278(1987) [PubMed] [Europe PMC] [Abstract]
  11. "Amino acid sequence of the 17-kilodalton fragment of the cytoplasmic region of the alpha-subunit of NA+,K+-ATPase."Dokl. Biochem. 288:270-272(1986)
  12. "Subcellular distribution and immunocytochemical localization of Na,K-ATPase subunit isoforms in human skeletal muscle."Mol. Membr. Biol. 11:255-262(1994) [PubMed] [Europe PMC] [Abstract]
  13. "An unappreciated role for RNA surveillance."Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
  14. "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."J. Proteome Res. 5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
  15. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  17. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  18. "POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters."Proc. Natl. Acad. Sci. U.S.A. 108:19234-19239(2011) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]