Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)

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PARK5; PGP9.5; Uch-L1; Neuron cytoplasmic protein 9.5; Ubiquitin thioesterase L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1

Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)
UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons.
Human UCH-L1 and the closely related protein UCHL3 have the most complicated knot structure yet discovered for a protein, with five knot crossings. It is speculated that a knot structure may increase a protein's resistance to degradation in the proteasome.Ubiquitin carboxy-terminal hydrolase L1 has been shown to interact with COP9 constitutive photomorphogenic homolog subunit 5.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG945Hu01Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAG945Hu01Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
MAG945Hu21Monoclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEG945MiELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)Enzyme-linked immunosorbent assay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG945Mu01Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)SDS-PAGE; WB; ELISA; IP.
RPG945Mu02Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAG945Mu01Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
PAG945Mu02Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEG945MiELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)Enzyme-linked immunosorbent assay

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG945Ra01Recombinant Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAG945Ra01Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
LAG945Ra71Biotin-Linked Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)IHC;WB;ELISA
LAG945Ra81FITC-Linked Polyclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)IHC;ICC;IF;WB
MAG945Ra21Monoclonal Antibody to Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSCG945RaCLIA Kit for Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)Chemiluminescent immunoassay
SEG945MiELISA Kit for Ubiquitin Carboxyl Terminal Hydrolase L1 (UCHL1)Enzyme-linked immunosorbent assay
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  25. ErratumAnn. Neurol. 55:899-899(2004)
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