MAS1 Oncogene (MAS1)
The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.MAS1-encoded protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about its oncogenic effects.Expression in Xenopus oocytes and a transfected mammalian cell line demonstrated that the MAS gene product is a functional angiotensin receptor.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant MAS1 Oncogene (MAS1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to MAS1 Oncogene (MAS1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to MAS1 Oncogene (MAS1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for MAS1 Oncogene (MAS1)CLIA Kit Customized Service Offer
n/aELISA Kit for MAS1 Oncogene (MAS1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant MAS1 Oncogene (MAS1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to MAS1 Oncogene (MAS1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to MAS1 Oncogene (MAS1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for MAS1 Oncogene (MAS1)CLIA Kit Customized Service Offer
n/aELISA Kit for MAS1 Oncogene (MAS1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant MAS1 Oncogene (MAS1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to MAS1 Oncogene (MAS1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to MAS1 Oncogene (MAS1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for MAS1 Oncogene (MAS1)CLIA Kit Customized Service Offer
n/aELISA Kit for MAS1 Oncogene (MAS1)ELISA Kit Customized Service Offer
  1. "Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains."Cell 45:711-719(1986) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The mas oncogene encodes an angiotensin receptor."Nature 335:437-440(1988) [PubMed] [Europe PMC] [Abstract]
  5. "G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor."Circulation 111:1806-1813(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS."J. Biol. Chem. 281:16757-16767(2006) [PubMed] [Europe PMC] [Abstract]