T-Box Protein 4 (TBX4)
TBX4 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.
The deduced protein contains 545 amino acids. Mouse and human TBX4 share more than 95% amino acid similarity overall, including 100% identity within the T-box region.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPH857Hu01Recombinant T-Box Protein 4 (TBX4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAH857Hu01Polyclonal Antibody to T-Box Protein 4 (TBX4)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for T-Box Protein 4 (TBX4)CLIA Kit Customized Service Offer
n/aELISA Kit for T-Box Protein 4 (TBX4)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant T-Box Protein 4 (TBX4)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to T-Box Protein 4 (TBX4)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to T-Box Protein 4 (TBX4)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for T-Box Protein 4 (TBX4)CLIA Kit Customized Service Offer
n/aELISA Kit for T-Box Protein 4 (TBX4)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant T-Box Protein 4 (TBX4)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to T-Box Protein 4 (TBX4)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to T-Box Protein 4 (TBX4)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for T-Box Protein 4 (TBX4)CLIA Kit Customized Service Offer
n/aELISA Kit for T-Box Protein 4 (TBX4)ELISA Kit Customized Service Offer
  1. "Virtual cloning and physical mapping of a human T-box gene, TBX4."Genomics 67:92-95(2000) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Mutations in the human TBX4 gene cause small patella syndrome."Am. J. Hum. Genet. 74:1239-1248(2004) [PubMed] [Europe PMC] [Abstract]