Goosecoid 2 (GSC2)

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GSCL; Homeobox protein goosecoid-like

Goosecoid 2 (GSC2)
Goosecoid like (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions.
Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Goosecoid 2 (GSC2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Goosecoid 2 (GSC2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Goosecoid 2 (GSC2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Goosecoid 2 (GSC2)CLIA Kit Customized Service Offer
n/aELISA Kit for Goosecoid 2 (GSC2)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Goosecoid 2 (GSC2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Goosecoid 2 (GSC2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Goosecoid 2 (GSC2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Goosecoid 2 (GSC2)CLIA Kit Customized Service Offer
n/aELISA Kit for Goosecoid 2 (GSC2)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Goosecoid 2 (GSC2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Goosecoid 2 (GSC2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Goosecoid 2 (GSC2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Goosecoid 2 (GSC2)CLIA Kit Customized Service Offer
n/aELISA Kit for Goosecoid 2 (GSC2)ELISA Kit Customized Service Offer
  1. "Characterization and mutation analysis of goosecoid-like (GSCL), a homeodomain-containing gene that maps to the critical region for VCFS/DGS on 22q11."Genomics 46:364-372(1997) [PubMed] [Europe PMC] [Abstract]
  2. "The DiGeorge syndrome minimal critical region contains a goosecoid-like (GSCL) homeobox gene that is expressed early in human development."Am. J. Hum. Genet. 60:1194-1201(1997) [PubMed] [Europe PMC] [Abstract]