Calreticulin 3 (CALR3)

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CRT2; CT93; Cancer/Testis Antigen 93; Calreticulin-2; Calsperin

Calreticulin 3 (CALR3)
Calreticulins, such as CALR3, are Ca(2+)-binding chaperones localized mainly in the endoplasmic/sarcoplasmic reticulum Persson et al. (2002).
Using database analysis to identify CALR-like sequences, Persson et al. (2002) identified mouse and human CALR3, which they designated CRT2. The deduced proteins contain 380 and 384 amino acids, respectively. CALR3 has an N-terminal endoplasmic reticulum (ER) signal sequence, followed by a globular N domain, 2 Ca(2+)-binding domains, a P domain, and a C domain, and it ends with an ER-retention motif (RNEL). The N-terminal region also contains 3 conserved cysteines. Northern blot analysis of several human tissues detected a 1.3-kb CALR3 transcript only in testis.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Calreticulin 3 (CALR3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Calreticulin 3 (CALR3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Calreticulin 3 (CALR3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Calreticulin 3 (CALR3)CLIA Kit Customized Service Offer
n/aELISA Kit for Calreticulin 3 (CALR3)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Calreticulin 3 (CALR3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Calreticulin 3 (CALR3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Calreticulin 3 (CALR3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Calreticulin 3 (CALR3)CLIA Kit Customized Service Offer
n/aELISA Kit for Calreticulin 3 (CALR3)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Calreticulin 3 (CALR3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Calreticulin 3 (CALR3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Calreticulin 3 (CALR3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Calreticulin 3 (CALR3)CLIA Kit Customized Service Offer
n/aELISA Kit for Calreticulin 3 (CALR3)ELISA Kit Customized Service Offer
  1. "Calreticulin-2 is localized in the lumen of the endoplasmic reticulum but is not a Ca2+ -binding protein."Histochem. Cell Biol. 135:531-538(2011) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of a novel calreticulin isoform (Crt2) in human and mouse."Gene 297:151-158(2002) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "Genetic screening of calcium regulation genes in familial hypertrophic cardiomyopathy."J. Mol. Cell. Cardiol. 43:337-343(2007) [PubMed] [Europe PMC] [Abstract]