ELAV Like Protein 1 (ELAVL1)

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ELAV1; HUR; Hua; MelG; Hu Antigen R; Embryonic Lethal,Abnormal Vision Like 1

ELAV Like Protein 1 (ELAVL1)
ELAVL1 is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.Like other ELAVL proteins, HuR has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. HuR was expressed ubiquitously, in contrast to the neural-specific expression of ELAVL2, ELAVL3, and ELAVL4.HuR associated with SIRT1 mRNA and enhanced its stability. In human diploid fibroblasts, they found a concomitant reduction in both HuR and SIRT1 during replicative senescence. Oxidative stress lowered SIRT1 mRNA and protein levels, caused the dissociation of HuR from SIRT1 mRNA, and reduced the stability of SIRT1 mRNA in an HuR-dependent manner.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant ELAV Like Protein 1 (ELAVL1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to ELAV Like Protein 1 (ELAVL1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to ELAV Like Protein 1 (ELAVL1)Polyclonal Antibody Customized Service Offer
Assay KitsSEJ780HuELISA Kit for ELAV Like Protein 1 (ELAVL1)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant ELAV Like Protein 1 (ELAVL1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to ELAV Like Protein 1 (ELAVL1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to ELAV Like Protein 1 (ELAVL1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for ELAV Like Protein 1 (ELAVL1)CLIA Kit Customized Service Offer
n/aELISA Kit for ELAV Like Protein 1 (ELAVL1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPJ780Ra01Recombinant ELAV Like Protein 1 (ELAVL1)SDS-PAGE; WB; ELISA; IP.
AntibodiesMAJ780Ra21Monoclonal Antibody to ELAV Like Protein 1 (ELAVL1)WB, ICC, IHC-P, IHC-F, ELISA
PAJ780Ra01Polyclonal Antibody to ELAV Like Protein 1 (ELAVL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEJ780RaELISA Kit for ELAV Like Protein 1 (ELAVL1)Enzyme-linked immunosorbent assay for Antigen Detection
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