AT-Rich Interactive Domain Containing Protein 1B (ARID1B)

[Edit]

BRIGHT; 6A3-5; BAF250b; DAN15; ELD/OSA1; p250R; BRG1-associated factor 250b; BRG1-binding protein hELD/OSA1; Osa homolog 2

AT-Rich Interactive Domain Containing Protein 1B (ARID1B)
ARID1B belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to AT-Rich Interactive Domain Containing Protein 1B (ARID1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for AT-Rich Interactive Domain Containing Protein 1B (ARID1B) ELISA Kit Customized Service Offer
  1. "SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones."J. Biol. Chem. 277:5498-5505(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "New 5'-(CGG)-3' repeats in the human genome."J. Biol. Chem. 273:30466-30471(1998) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats."Nat. Genet. 14:285-291(1996) [PubMed] [Europe PMC] [Abstract]
  5. "Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors."J. Biol. Chem. 277:41674-41685(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner."Mol. Cell. Biol. 23:2942-2952(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein."Biochem. J. 364:255-264(2002) [PubMed] [Europe PMC] [Abstract]
  8. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  15. "Haploinsufficiency of ARID1B, a member of the SWI/SNF-a chromatin-remodeling complex, is a frequent cause of intellectual disability."Am. J. Hum. Genet. 90:565-572(2012) [PubMed] [Europe PMC] [Abstract]
  16. "Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome." Nat. Genet. 44:376-378(2012) [PubMed] [Europe PMC] [Abstract]
  17. "Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome."Nat. Genet. 44:379-380(2012) [PubMed] [Europe PMC] [Abstract]
  18. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  19. "Recent advances in understanding chromatin remodeling by SWI/SNF complexes."Curr. Opin. Genet. Dev. 13:136-142(2003) [PubMed] [Europe PMC] [Abstract]
  20. "Two related ARID family proteins are alternative subunits of human SWI/SNF complexes."Biochem. J. 383:319-325(2004) [PubMed] [Europe PMC] [Abstract]
  21. "The DNA-binding properties of the ARID-containing subunits of yeast and mammalian SWI/SNF complexes."Nucleic Acids Res. 32:1345-1353(2004) [PubMed] [Europe PMC] [Abstract]
  22. "Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex."Genes Dev. 22:2370-2384(2008) [PubMed] [Europe PMC] [Abstract]
  23. "Crystal structure of the HBAF250B AT-rich interaction domain (ARID)."Submitted (OCT-2006) to the PDB data bank
  24. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]