Wingless Type MMTV Integration Site Family, Member 3 (WNT3)
[Edit]INT4; Proto-oncogene Int-4 homolog
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3 is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL818Hu01 | Recombinant Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAL818Hu01 | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | WB; IHC; ICC; IP. |
| MAL818Hu21 | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEL818Hu | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCL818Hu | CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL818Ra01 | Recombinant Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAL818Ra21 | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | WB; IHC; ICC; IP. |
| PAL818Ra01 | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEL818Ra | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL818Bo01 | Recombinant Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 3 (WNT3) | ELISA Kit Customized Service Offer |
- "Molecular cloning and characterization of human WNT3."Int. J. Oncol. 19:977-982(2001) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene."Genomics 17:790-792(1993) [PubMed] [Europe PMC] [Abstract]
- "Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family."Am. J. Hum. Genet. 74:558-563(2004) [PubMed] [Europe PMC] [Abstract]