TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)

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ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; Connection to IKK and SAPK/JNK; Nuclear factor NF-kappa-B activator 1; TRAF3-interacting protein 2

TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)
TRAF3IP2 involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)CLIA Kit Customized Service Offer
n/aELISA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)CLIA Kit Customized Service Offer
n/aELISA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)CLIA Kit Customized Service Offer
n/aELISA Kit for TNF Receptor Associated Factor 3 Interacting Protein 2 (TRAF3IP2)ELISA Kit Customized Service Offer
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  11. "An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis."Immunity 39:676-686(2013) [PubMed] [Europe PMC] [Abstract]