Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP)

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INAG1; RIAM; RARP1; APBB1-interacting protein; Proline-rich EVH1 ligand; Rap1-GTP-interacting adapter molecule; Retinoic acid-responsive proline-rich protein

Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP)
The deduced 666-amino acid protein contains an N-terminal proline-rich domain, a RAS-associated domain, a PH domain, and a long C-terminal proline-rich domain. Northern blot analysis detected a 2.6-kb transcript in most tissues, with highest expression in thymus, spleen, liver, and peripheral leukocytes. RNA dot blot analysis detected RARP1 preferentially expressed in thymus, spleen, lymph node, bone marrow, and peripheral leukocytes. Western blot analysis showed that endogenous promyeloleukemic cell RARP1 has an apparent molecular mass of 110 kD. Immunostaining of transfected Chinese hamster ovary cells found RARP1 localized to the cytoplasm. Endogenous mouse Rarp1 was found in the cytoplasm of megakaryocytes or their progenitor cells in bone marrow and spleen.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM488Hu01 Recombinant Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM488Hu01 Polyclonal Antibody to Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amyloid Beta Precursor Protein Binding B1 Interacting Protein (APBB1IP) ELISA Kit Customized Service Offer
  1. "The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells."J. Biol. Chem. 278:51685-51692(2003) [PubMed] [Europe PMC] [Abstract]
  2. "RIAM, an Ena/VASP and profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion."Dev. Cell 7:585-595(2004) [PubMed] [Europe PMC] [Abstract]
  3. "PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins."FEBS Lett. 579:455-463(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  10. "RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover."J. Biol. Chem. 288:8238-8249(2013) [PubMed] [Europe PMC] [Abstract]