Proteasome 26S Subunit, Non ATPase 8 (PSMD8)

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S14; Nin1p; p31; HIP6; HYPF; Rpn12; 26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit RPN12

Proteasome 26S Subunit, Non ATPase 8 (PSMD8)
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD8 encodes a non-ATPase subunit of the 19S regulator.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPP778Hu21 OVA Conjugated Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Immunogen; SDS-PAGE; WB.
RPP778Hu01 Recombinant Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP778Hu08 Polyclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) WB; IHC; ICC; IP.
PAP778Hu01 Polyclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome 26S Subunit, Non ATPase 8 (PSMD8) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae."EMBO J. 14:3105-3115(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Mass spectrometric characterization of the affinity-purified human 26S proteasome complex."Biochemistry 46:3553-3565(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]