NK2 Homeobox Protein 3 (NKX2-3)

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NKX2C; NKX2.3; CSX3; NKX4-3; NK2 Transcription Factor Related Protein, Locus 3; Homeobox protein NK-2 homolog C

NK2 Homeobox Protein 3 (NKX2-3)
NKX2-3 is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.Nkx2.3 contains a homeobox, a conserved NK2 domain, a C-terminal GIRAW motif typical of NKX2 proteins, and an N-terminal homology domain conserved among NK2 genes. RT-PCR and whole-mount in situ hybridization analyses detected Nkx2.3 expression primarily in gut mesoderm, distinct regions of the branchial arches, the tongue epithelium, and limited domains in the developing jaws, possibly including tooth anlagen.Nkx2.3 deficiency resulted in severe morphologic alterations in gut and spleen with early postnatal lethality in the majority of homozygous mutants.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant NK2 Homeobox Protein 3 (NKX2-3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)CLIA Kit Customized Service Offer
n/aELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant NK2 Homeobox Protein 3 (NKX2-3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)CLIA Kit Customized Service Offer
n/aELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant NK2 Homeobox Protein 3 (NKX2-3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to NK2 Homeobox Protein 3 (NKX2-3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for NK2 Homeobox Protein 3 (NKX2-3)CLIA Kit Customized Service Offer
n/aELISA Kit for NK2 Homeobox Protein 3 (NKX2-3)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]