Multiple EGF Like Domains Protein 8 (MEGF8)

[Edit]

SBP1; EGFL4; SBP1; C19orf49; HBV Pre s2 Binding Protein 1; Multiple epidermal growth factor-like domains protein 8; Epidermal growth factor-like protein 4

Multiple EGF Like Domains Protein 8 (MEGF8)
EGF-like domains are believed to play a critical role in a number of extracellular events, including cell adhesion and receptor-ligand interactions. Proteins with EGF-like domains often consist of more than 1,000 amino acids, have multiple copies of the EGF-like domain, and contain additional domains known to be involved in specific protein-protein interactions. To identify proteins containing EGF-like domains, Nakayama et al. (1998) searched a database of long cDNA sequences randomly selected from a human brain cDNA library for those that encode an EGF-like motif. They identified several partial cDNAs encoding novel proteins with EGF-like domains, such as EGFL4, which they named MEGF8. The predicted partial EGFL4 protein has a laminin-type EGF-like domain, 5 EGF-like domains, and a transmembrane domain.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Multiple EGF Like Domains Protein 8 (MEGF8)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)CLIA Kit Customized Service Offer
n/aELISA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Multiple EGF Like Domains Protein 8 (MEGF8)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)CLIA Kit Customized Service Offer
n/aELISA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Multiple EGF Like Domains Protein 8 (MEGF8)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Multiple EGF Like Domains Protein 8 (MEGF8)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)CLIA Kit Customized Service Offer
n/aELISA Kit for Multiple EGF Like Domains Protein 8 (MEGF8)ELISA Kit Customized Service Offer
  1. "Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening."Genomics 51:27-34(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization."Am. J. Hum. Genet. 91:897-905(2012) [PubMed] [Europe PMC] [Abstract]