RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)

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RPAC2; RPA16; RPO1-3; RPC16; RPA9; DNA-directed RNA polymerases I and III subunit RPAC2; RNA polymerase I 16 kDa subunit

RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)
The peak region of 13q contains POLR1D, a subunit of both RNA polymerases I and III. RNA polymerase I is involved in the production of 18S, 5.8S, and 28S rRNAs, while RNA polymerase III synthesizes small essential RNAs, such as tRNAs, 5S rRNA, and some snRNAs.There is not much information regarding this gene in the literature. POLR1D is overexpressed in 42% of the primary tumors, showing high correlation between expression and copy number.
RPA16 cDNA encoding the 16-kDa subunit of mouse RNA polymerase I by a yeast two-hybrid system using mRPA40 as a bait. The deduced amino acid sequence shows 45% identity to the yeast subunit of RNA polymerases I and III, known to associate with AC40, and a local similarity to bacterial alpha subunit.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)CLIA Kit Customized Service Offer
n/aELISA Kit for RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)CLIA Kit Customized Service Offer
n/aELISA Kit for RNA Polymerase I, DNA Directed Polypeptide D (POLR1D)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]