Kinesin Family, Member 6 (KIF6)
The 719Arg allele of KIF6 was associated with coronary events in Caucasian participants of five prospective studies. KIF6 variant was associated with non-fatal myocardial infarction (MI) in a case-control study of an admixed population from the Central Valley of Costa Rica. Genotypes of the KIF6 variant were determined for 4,134 men and women.
The 719Arg variant of Trp719Arg, a polymorphism in kinesin-like protein 6, is associated with greater risk of coronary events and greater benefit from pravastatin versus placebo. The benefit of intensive therapy in carriers was significant as early as day 30 of therapy. Carriers and noncarriers did not differ in on-treatment low-density lipoprotein cholesterol, triglyceride, or C-reactive protein (CRP) levels.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Kinesin Family, Member 6 (KIF6)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Kinesin Family, Member 6 (KIF6)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Kinesin Family, Member 6 (KIF6)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Kinesin Family, Member 6 (KIF6)CLIA Kit Customized Service Offer
n/aELISA Kit for Kinesin Family, Member 6 (KIF6)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Kinesin Family, Member 6 (KIF6)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Kinesin Family, Member 6 (KIF6)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Kinesin Family, Member 6 (KIF6)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Kinesin Family, Member 6 (KIF6)CLIA Kit Customized Service Offer
n/aELISA Kit for Kinesin Family, Member 6 (KIF6)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Kinesin Family, Member 6 (KIF6)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Kinesin Family, Member 6 (KIF6)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Kinesin Family, Member 6 (KIF6)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Kinesin Family, Member 6 (KIF6)CLIA Kit Customized Service Offer
n/aELISA Kit for Kinesin Family, Member 6 (KIF6)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]