Phosphatidylinositol Glycan O (PIGO)

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Phosphatidylinositol Glycan Anchor Biosynthesis,Class O; GPI ethanolamine phosphate transferase 3

Phosphatidylinositol Glycan O (PIGO)
Pigo knockout F9 embryonal carcinoma cells expressed very little GPI-anchored proteins and accumulated the same major GPI intermediate as the mouse class F mutant cell, which is defective in transferring phosphoethanolamine to the third mannose due to mutant Pig-f gene. PIG-O and PIG-F proteins associate with each other, and the stability of PIG-O was dependent upon PIG-F.The class F cell is completely deficient in the surface expression of GPI-anchored proteins. A minor GPI intermediate seen in Pig-o knockout but not class F cells had more than three mannoses with phosphoethanolamines on the first and third mannoses, suggesting that this GPI may account for the low expression of GPI-anchored proteins.Mammalian cells have redundant activities in transferring phosphoethanolamine to the third mannose, both of which require PIG-F.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Phosphatidylinositol Glycan O (PIGO)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Phosphatidylinositol Glycan O (PIGO)CLIA Kit Customized Service Offer
n/aELISA Kit for Phosphatidylinositol Glycan O (PIGO)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Phosphatidylinositol Glycan O (PIGO)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Phosphatidylinositol Glycan O (PIGO)CLIA Kit Customized Service Offer
n/aELISA Kit for Phosphatidylinositol Glycan O (PIGO)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Phosphatidylinositol Glycan O (PIGO)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Phosphatidylinositol Glycan O (PIGO)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Phosphatidylinositol Glycan O (PIGO)CLIA Kit Customized Service Offer
n/aELISA Kit for Phosphatidylinositol Glycan O (PIGO)ELISA Kit Customized Service Offer
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