KIF1 Binding Protein (KBP)

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TTC20; KIAA1279

KIF1 Binding Protein (KBP)
KBP encodes a 621-amino acid protein that shares 89% sequence homology with the mouse homolog. The predicted protein contains 2 tetratricopeptide repeats (TPR). Northern blot analysis of adult and fetal tissues detected expression of a 2.4-kb transcript in all tissues except blood leukocytes. The transcript was present in different parts of the adult central nervous system, including cerebellum, cortex, medulla, spinal cord, occipital lobe, frontal lobe, temporal lobe, and putamen.
The deduced protein contains 632 amino acids. RT-PCR detected high expression in heart, brain, ovary, testis, spinal cord, and all specific brain regions examined. Moderate expression was detected in all other adult tissues examined, as well as in fetal liver and brain.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant KIF1 Binding Protein (KBP)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to KIF1 Binding Protein (KBP)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to KIF1 Binding Protein (KBP)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for KIF1 Binding Protein (KBP)CLIA Kit Customized Service Offer
n/aELISA Kit for KIF1 Binding Protein (KBP)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant KIF1 Binding Protein (KBP)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to KIF1 Binding Protein (KBP)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to KIF1 Binding Protein (KBP)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for KIF1 Binding Protein (KBP)CLIA Kit Customized Service Offer
n/aELISA Kit for KIF1 Binding Protein (KBP)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant KIF1 Binding Protein (KBP)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to KIF1 Binding Protein (KBP)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to KIF1 Binding Protein (KBP)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for KIF1 Binding Protein (KBP)CLIA Kit Customized Service Offer
n/aELISA Kit for KIF1 Binding Protein (KBP)ELISA Kit Customized Service Offer
  1. "The novel protein KBP regulates mitochondria localization by interaction with a kinesin-like protein."BMC Cell Biol. 6:35-35(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Homozygous nonsense mutations in KIAA1279 are associated with malformations of the central and enteric nervous systems."Am. J. Hum. Genet. 77:120-126(2005) [PubMed] [Europe PMC] [Abstract]
  9. "KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to microtubule dynamics and neuronal differentiation."Hum. Mol. Genet. 19:3642-3651(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "KBP-cytoskeleton interactions underlie developmental anomalies in Goldberg-Shprintzen syndrome."Hum. Mol. Genet. 22:2387-2399(2013) [PubMed] [Europe PMC] [Abstract]