Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)

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Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)
ACSF3, Belongs to the ATP-dependent AMP-binding enzyme family. Acyl-coenzyme A synthetases (ACSs) catalyze the fundamental, initial reaction in fatty acid metabolism. "Activation" of fatty acids by thioesterification to CoA allows their participation in both anabolic and catabolic pathways. The availability of the sequenced human genome has facilitated the investigation of the number of ACS genes present. Using two conserved amino acid sequence motifs to probe human DNA databases, 26 ACS family genes/proteins were identified. ACS activity in either humans or rodents was demonstrated previously for 20 proteins, but 6 remain candidate ACSs. For two candidates, cDNA was cloned, protein was expressed in COS-1 cells, and ACS activity was detected.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)CLIA Kit Customized Service Offer
n/aELISA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)CLIA Kit Customized Service Offer
n/aELISA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)CLIA Kit Customized Service Offer
n/aELISA Kit for Acyl Coenzyme A Synthetase Family, Member 3 (ACSF3)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome."J. Lipid Res. 48:2736-2750(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria." Nat. Genet. 43:883-886(2011) [PubMed] [Europe PMC] [Abstract]