Rhox Homeobox Family, Member 2B (RHOXF2B)

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Rhox Homeobox Family, Member 2B (RHOXF2B)
Genes of the Rhox gene family from a gene cluster on the mammalian X chromosome. The mouse Rhox cluster has 32 genes; the human cluster has three genes: RHOXF1, RHOXF2 and RHOXF2B. The latter two are extremely closely related and most likely a very recent tandem duplication. It is unclear if all three genes are functional. The Rhox genes are not present in Drosophila or amphioxus.
The Rhox cluster genes targeted for H1-mediated transcriptional repression are also subject to another DNA methylation-regulated process: Xp imprinting. Rhox gene cluster is a major target of H1-mediated transcriptional repression in ES cells and that H1 is a candidate to have a role in Xp imprinting. The rhox homeobox gene cluster is imprinted and selectively targeted for regulation by histone h1 and DNA methylation.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Rhox Homeobox Family, Member 2B (RHOXF2B)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Rhox Homeobox Family, Member 2B (RHOXF2B)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Rhox Homeobox Family, Member 2B (RHOXF2B)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Rhox Homeobox Family, Member 2B (RHOXF2B)CLIA Kit Customized Service Offer
n/aELISA Kit for Rhox Homeobox Family, Member 2B (RHOXF2B)ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]