Rat Model for Necrotizing Enterocolitis (NEC)

  • Product No.DSI730Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by artificial feeding and induction of hypoxia and cold stimulation
  • Model Animal StrainsNeonatal SD rats(SPF), 2 days old
  • Modeling Grouping1.Randomly divided into six group: Control group, Model group, Positive drug group and Te
  • Modeling Period1~2 weeks
  • Modeling Method1. The birth of 2 day's neonatal SD rats and separated from maternal rats, using the self-made 24 G closed venous indwelling needle to connect with the 1 ml injector instead of the gastric tube to feed the milk,feed the tats 4 times a day by oral intubation, each intubation depth of about 2 cm.The first feeding amount was 0.1 ml/ times, every 24 hours increased by 0.1ml/ times, after 48 hours gradually increased to the amount of 0.3 ml/ times.
    2. After feeding 2 times a day, the newborn SD rats were placed in the self-made hypoxia cabin, zero oxygen measuring instrument, input the neonatal rat to the nitrogen (15 L/min flow) for 90 s, and then a self-made 4 degrees cold box for 10 min continuous cold stimulation.
    3. NEC model of neonatal SD rats was established for 3 days continuously. The rats were sacrificed at 12 h after the last feeding.
  • ApplicationsDisease Model
  • Downloadn/a
  • UOM Each case
  • FOB US$ 150 
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

GIVEAWAYS

INCREMENT SERVICES

Catalog No. Related products for research use of Rattus norvegicus (Rat) Organism species Applications (RESEARCH USE ONLY!)
DSI730Ra01 Rat Model for Necrotizing Enterocolitis (NEC) Disease Model