Recombinant Low Density Lipoprotein Receptor Related Protein 1 (LRP1)

CD91; LRP; A2MR; APOER; APR; TGFBR5; Alpha-2-Macroglobulin Receptor; Prolow-density lipoprotein receptor-related protein 1; Apolipoprotein E receptor

  • Product No.RPB010Hu02
  • Organism SpeciesHomo sapiens (Human) Same name, Different species.
  • SourceProkaryotic expression
  • HostE.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Nucleus, Golgi apparatus
  • Predicted Molecular Mass49.2kDa
  • Accurate Molecular Mass49kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla20~Asp429 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder
  • Purity> 80%
  • Isoelectric Point4.7
  • Applications Positive Control; Immunogen; SDS-PAGE; WB.
    If bio-activity of the protein is needed, please check active protein.
  • DownloadInstruction Manual
  • UOM 10µg50µg 200µg 1mg 5mg
  • FOB US$ 138  US$ 345  US$ 690  US$ 2070  US$ 5175 
    For more details, please contact local distributors!

SEQUENCE

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

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Magazine Citations
European Journal of Vascular and Endovascular Surgery Plasma Low-density Lipoprotein Receptor-related Protein 1 Concentration is not Associated with Human Abdominal Aortic Aneurysm Presence Science: Article
Int J Cardiol Circulating soluble low-density lipoprotein receptor-related protein 1 (sLRP1) concentration is associated with hypercholesterolemia: A new potential biomarker for atherosclerosis PubMed: 26285183
International Journal of Cardiology Circulating levels of soluble low-density lipoprotein receptor-related protein 1 (sLRP1) as novel biomarker of epicardial adipose tissue pubmed:27543712
Journal of Cellular and Molecular Medicine Extracellular vesicles do not contribute to higher circulating levels of soluble LRP1 in idiopathic dilated cardiomyopathy doi:10.1111
Scientific Reports Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus Pubmed:29348672
Atherosclerosis Soluble low-density lipoprotein receptor-related protein 1 as a biomarker of coronary risk: Predictive capacity and association with clinical events
Biomedical Reports Gender difference and genetic variance in lipoprotein receptor‑related protein 1 is associated with mortality
biorxiv. CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signaling
JCI Insight CMTM6 drives cisplatin resistance by regulating Wnt signaling through ENO-1/AKT/GSK3¦Â axis 33434185