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Top-Ranked ELISA Kits (Procollagen III N-Terminal Propeptide PIIINP). Vol.8 (2019)
Procollagen III N-Terminal Propeptide (PIIINP) is an amino-terminal peptide produced by cleavage of Aminoterminus peptidasebefore liver cell to extracellular deposition. During this process, PIIINP and type III collagen present the same molecular mass andenter the blood circulation. Therefore, it can be used as an indicator to detect the synthesis of type III collagen. During thedevelopment of cirrhosis, the level of PIIINP(50KD) in serum will increase, and it has a significant positive correlation with the degreeof liver fibrosis. Clinical study found that the level of PIIINP is also associated with liver inflammation and cancer to some extent,especially in patients with primary and m......
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Top-Ranked ELISA Kits (Procollagen I N-Terminal Propeptide PINP). Vol.7 (2019)
Skeletal type I collagen is the most abundant form of collagen in the human body, accounting for about 90% ofbone mass. Type I collagen is mainly synthesized in bone tissue. The first synthesis is procollagen. There is anextended peptide at the N-terminal and C-terminal of the type I procollagen, which is called type I procollagenN-terminal propeptide (PINP). And type I procollagen C-terminal propeptide (PICP); when type I procollagen issecreted outside the cell by osteoblasts, the N-terminal and C-terminal prolonged peptides are cleaved byproteases, except for a small amount deposited in the bone matrix, a large number will enter the blood circulationand eventually be cleared by the l......
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Top-Ranked ELISA Kits (Brain Natriuretic Peptide BNP). Vol.6 (2019)
Brain Natriuretic Peptide (BNP), also known as B-type Natriuretic Peptide, which is mainly synthesized and secreted by ventricularmyocytes. The main factors to stimulate BNP secretion are the changes in ventricular load and wall tension. It plays a significant rolein regulating the homeostasis of blood pressure and blood volume, diuresis and so on. BNP is species-specific. Rat BNP iscomposed of 45 amino acids, while pig, dog, and human BNP are composed of 32 amino acids. The gene fragment of human BNP islocated at the distal end of the short arm of chromosome 1 and is linked to the upstream ANP fragment. its reverse transcriptionaldeoxyribonucleic acid (cDNA) consists of 1900 nucleotid......
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Literature of Cloud Clone products in July 2019 (Excerpt)
In July 2019, Literature of Cloud Clone products has exceeded 240. Cloud-Clone could provide multipleproteins, antibodies and ELISA kit, which has been praised by customers. (For more information, please visit: www.cloud-clone.com/www.uscnk.cn)
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Top-Ranked ELISA Kits (Insulin INS). Vol.5 (2019)
Insulin is a protein hormone secreted by islet beta cells in the pancreas. Insulin is involved in regulating glucosemetabolism and controlling blood sugar balance. It can be used to treat diabetes mellitus. The main physiologicalfunction of insulin is to regulate the metabolic process. Glucose metabolism: promoting the uptake and utilizationof glucose by tissue cells, promoting glycogen synthesis, inhibiting gluconeogenesis and lowering blood sugar;Fat metabolism: promoting fatty acid synthesis and fat storage, reducing fat decomposition; Protein: acceleratingthe entry of amino acids into cells, promoting all links of protein synthesis to increase protein Quality synthesis.Insulin is t......
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Top-Ranked ELISA Kits (Testosterone Testo). Vol.4 (2019)
Testosterone is a steroid hormone secreted by male testes or female ovaries. The adrenal gland also secretes asmall amount of testosterone, which has two effects on humans and other vertebrates: directly or in the form ofserum DHT to activate androgen receptors; and converted to estradiol to activate some estrogen receptors. Freetestosterone is transported to the cytoplasm of target tissue cells, binds to androgen receptors, or is converted toserum DHT by 5a-reductase. DHT also binds to androgen receptors (which are more stable, and the malehormone intensity of DHT is about 2.5 times that of testosterone). Testosterone receptors or serum DHTreceptors undergo structural changes that all......