Interferon Gamma (IFNg)

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IFN-G; IFG; IFI; INFr; IFN, Immune Interferon

Interferon Gamma (IFNg)

Interferon gamma (IFN-gama ) is a multifunctional protein first observed as an antiviral activity in cultures of Sindbis virus-infected leukocytes stimulated by PHA . Produced by T lymphocytes and natural killer (NK) cells, IFN-γ is now known to be both an inhibitor of viral replication and a regulator of numerous immunological functions.

IFN-γ influences the class of antibody produced by B cells, upregulates class I and II MHC complex antigens and increases. the efficiency of macrophage-mediated killing of intracellular parasites. Most of the activities attributed to IFN-γ are believed to be mediated by IFN-γ-induced proteins. The appearance of such proteins is a consequence of IFN-γ binding to a specific receptor that is distinct from the receptor for IFN-αandβ.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Hu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Hu61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Hu61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Hu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Hu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Hu22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Hu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Hu81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Hu06 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Hu26 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Hu72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Hu82 FITC-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Hu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Hu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Hu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.
AEA049Hu ELISA Kit for Anti-Interferon Gamma Antibody (Anti-IFNg) Enzyme-linked immunosorbent assay for Antibody Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Mu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
RPA049Mu02 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Mu61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Mu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Mu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Mu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Mu81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Mu02 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Mu06 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Mu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Mu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Mu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.
HEA049Mu High Sensitive ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ra01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
RPA049Ra02 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Ra61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Ra61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
APA049Ra01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Ra01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ra71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ra81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
PAA049Ra02 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ra21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Ra06 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Ra ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ra CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Gu01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Gu01 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Gu01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Gu21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Gu91 HRP-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Gu71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Gu ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Gu CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Rb01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
RPA049Rb02 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
EPA049Rb61 Eukaryotic Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
APA049Rb61 Active Interferon Gamma (IFNg) Cell culture; Activity Assays.
Antibodies PAA049Rb52 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Rb51 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Rb22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Rb71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Rb81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Rb21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Rb56 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Rb72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Rb ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Rb CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Si01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Si01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Si21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Si ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Si CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ca01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ca01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ca21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Ca ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ca CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Po01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Po01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Po21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Po ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Po CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Bo01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Bo01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Bo21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Bo ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Bo CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ov01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ov01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ov71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ov81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Ov21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interferon Gamma (IFNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Gamma (IFNg) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Eq01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAA049Eq21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
PAA049Eq01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits SEA049Eq ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Ga01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Ga01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
MAA049Ga22 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ga71 Biotin-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
LAA049Ga81 FITC-Linked Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IF.
MAA049Ga21 Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
LAA049Ga72 Biotin-Linked Monoclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC.
Assay Kits SEA049Ga ELISA Kit for Interferon Gamma (IFNg) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA049Ga CLIA Kit for Interferon Gamma (IFNg) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA049Fi01 Recombinant Interferon Gamma (IFNg) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA049Fi01 Polyclonal Antibody to Interferon Gamma (IFNg) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interferon Gamma (IFNg) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Gamma (IFNg) ELISA Kit Customized Service Offer
  1. "Structure of the human immune interferon gene."Nature 298:859-863(1982) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of human immune interferon cDNA in E. coli and monkey cells."Nature 295:503-508(1982) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and expression of a novel variant of human interferon-gamma cDNA."J. Biochem. 97:153-159(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and structure of the human immune interferon-gamma chromosomal gene."EMBO J. 1:953-958(1982) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells."Nucleic Acids Res. 10:2487-2501(1982) [PubMed] [Europe PMC] [Abstract]
  6. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome." Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation."J. Biol. Chem. 259:6790-6797(1984) [PubMed] [Europe PMC] [Abstract]
  9. "Structural characterization of human interferon gamma. Heterogeneity of the carboxyl terminus."Eur. J. Biochem. 166:145-149(1987) [PubMed] [Europe PMC] [Abstract]
  10. "Studies on the sugar chains of interferon-gamma from human peripheral-blood lymphocytes."J. Biochem. 105:1034-1039(1989) [PubMed] [Europe PMC] [Abstract]
  11. "Three-dimensional structure of recombinant human interferon-gamma."Science 252:698-702(1991) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor."Nature 376:230-235(1995) [PubMed] [Europe PMC] [Abstract]
  13. "Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma."J. Mol. Biol. 299:169-179(2000) [PubMed] [Europe PMC] [Abstract]
  14. "Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex."Structure 8:927-936(2000) [PubMed] [Europe PMC] [Abstract]
  15. "1H, 13C, and 15N NMR backbone assignments and secondary structure of human interferon-gamma."Biochemistry 31:8180-8190(1992) [PubMed] [Europe PMC] [Abstract]
  16. "Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population."Br. J. Haematol. 126:682-685(2004) [PubMed] [Europe PMC] [Abstract]