Melatonin alleviates Ochratoxin A-induced liver inflammation
On 26 January, 2021, professor Wence Wang from South China Agricultural University published a paper on Journal of Hazardous Materials. The paper titled Melatonin alleviates Ochratoxin A-induced liver inflflammation involved intestinal microbiota homeostasis and microbiota-independent mannerMelatonin (MEL) shows an anti-inflflammatory effffect and regulates intestinal microbiota communities in animals and humans; Ochratoxin A (OTA) induces liver inflflammation through intestinal microbiota. However, it remains to know whether MEL alleviates the liver inflflammation induced by OTA. In this study, MEL reversed various adverse effffects induced by OTA. MEL recovered the swarming and motil......
Literature of Cloud Clone products in Mar. 2021 (Excerpt)
In Mar. 2021, Literature of Cloud Clone products has exceeded 180. Cloud-Clone could provide multipleproteins, antibodies and ELISA kit, which has been praised by customers.
Four advantages of Cloud-Clone Antibodies
CLOUD-CLONE CORP. (CCC, USA), a research and experimental development in molecular biology and immunology oriented company headquartered in Houston, is the owner of the trade mark “Cloud-Clone”. It has certified with ISO 9001:2015 and ISO 13485:2016.1. Original Manufacturer for Antibodies 2. Antibodies validated by Knock-out platformThe Knock-out validation platform is the only recognized gold standard platform for antibody detection. It reduces or blocks the target gene expression through gene interference or knockout technology, so as to detecte the accuracy of antibody to recognize the target protein. The Knock-out validation platform is also the main direction of Cloud-Clone, a......
Five advantages of Cloud-Clone Antibodies
Biomarkers of nucleic acid oxidation – A summary state-of-the-art
On 18 February, 2021, professor Marcus S. Cooke from Department of Occupational Safety and Health, Chung Shan Medical University published a paper on Redox Biology. The paper titled Biomarkers of nucleic acid oxidation ‒ A summary state-of-the-art.Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide variety of diseases. Increasingly, interest is also focusing upon the effffects of damage to the other nucleic acids, RNA and the (2′-deoxy-)ribonucleotide pools, and evidence is growing that these too may have an important role in disease. LC-MS/MS has the ability to provide absolute quantifification of specifific biomarkers, such as 8-oxo-7,8-dihydro......
POLRMT mutations impair mitochondrial transcription causing neurological disease
On 18 February, 2021, professor Robert W.Taylor from Newcastle University and Claes M.Gustafsson from University of Gothenburg published a paper on Nature communications. The paper titled POLRMT mutations impair mitochondrial transcription causing neurological disease.While >300 disease-causing variants have been identifified in the mitochondrial DNA (mtDNA) polymerase γ, no mitochondrial phenotypes have been associated with POLRMT, the RNA polymerase responsible for transcription of the mitochondrial genome. Here, we characterise the clinical and molecular nature of POLRMT variants in eight individuals from seven unrelated families. Patients present with global developmental delay......