B-Cell Leukemia/Lymphoma 2 (Bcl2)

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B-Cell CLL/Lymphoma 2

B-Cell Leukemia/Lymphoma 2 (Bcl2)

Bcl-2) was one of the first oncogenic proteins discovered to inhibit apoptosis. The Bcl-2 family of proteins plays a crucial role in the regulation of cell death in many eukaryotic systems. Bcl-2 is a 26 kD protein associated with cell survival.

Bcl-2 is localized within the outer mitochondrial membrane, endoplasmic reticulum, and the nuclear envelope, where it exerts cell survival functions within many cell types. These functions include ion-conducting channel formation, integral protection from cytotoxic agents, inhibition of proteins that activate caspases responsible for disassembling cells, as well as the ability to modulate cell cycle initiation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA778Hu01 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA778Hu01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
MAA778Hu22 Monoclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
LAA778Hu71 Biotin-Linked Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC.
LAA778Hu81 FITC-Linked Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IF.
MAA778Hu21 Monoclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits SEA778Hu ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA778Hu CLIA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA778Mu01 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA778Mu02 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA778Mu01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
LAA778Mu71 Biotin-Linked Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC.
LAA778Mu81 FITC-Linked Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IF.
PAA778Mu02 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits SEA778Mu ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA778Ra01 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA778Ra01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
LAA778Ra81 FITC-Linked Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IF.
MAA778Ra21 Monoclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits SEA778Ra ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) CLIA Kit Customized Service Offer
n/a ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA778Po01 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA778Po01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) CLIA Kit Customized Service Offer
n/a ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA778Bo01 Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA778Bo01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
MAA778Bo21 Monoclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits SEA778Bo ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2) Recombinant Protein Customized Service Offer
Antibodies PAA778Ov01 Polyclonal Antibody to B-Cell Leukemia/Lymphoma 2 (Bcl2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) CLIA Kit Customized Service Offer
n/a ELISA Kit for B-Cell Leukemia/Lymphoma 2 (Bcl2) ELISA Kit Customized Service Offer
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  23. "Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2."Cancer Res. 69:6782-6789(2009) [PubMed] [Europe PMC] [Abstract]
  24. "Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect."J. Biol. Chem. 284:9692-9699(2009) [PubMed] [Europe PMC] [Abstract]
  25. "Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells."Biochem. Biophys. Res. Commun. 401:231-237(2010) [PubMed] [Europe PMC] [Abstract]
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  28. "Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma."Proc. Natl. Acad. Sci. U.S.A. 110:3943-3948(2013) [PubMed] [Europe PMC] [Abstract]
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