Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1)

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HNRPA1; hnRNP-A1; Helix-destabilizing protein; Single-strand RNA-binding protein; hnRNP core protein A1; Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed

Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1)

Heterogeneous nuclear ribonucleoprotein A1  belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). This protein is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC252Hu01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC252Hu01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC252Mu01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC252Mu01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) ELISA Kit Customized Service Offer
  1. "Isolation of an active gene encoding human hnRNP protein A1. Evidence for alternative splicing."J. Mol. Biol. 207:491-503(1989) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms."Nucleic Acids Res. 16:3751-3770(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1."EMBO J. 5:2267-2273(1986) [PubMed] [Europe PMC] [Abstract]
  7. , Submitted (DEC-2008) to UniProtKB