Nuclear Transport Factor 2 (NUTF2)

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NTF2; PP15; Placental protein 15

Nuclear Transport Factor 2 (NUTF2)
Nuclear transport factor 2 is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62. This encoded protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It is thought to be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. NTF2 is required for the nuclear import and reaccumulation of RAN, a molecule that is depleted from the nucleus as RAN-GTP complexed with exported cargo. By mutation analysis and biochemical studies, they determined that nuclear reaccumulation of RAN is mediated by direct interaction between the 2 proteins and that RAN-GDP is the species bound and transported by NTF2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC671Hu01 Recombinant Nuclear Transport Factor 2 (NUTF2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC671Hu01 Polyclonal Antibody to Nuclear Transport Factor 2 (NUTF2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Nuclear Transport Factor 2 (NUTF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transport Factor 2 (NUTF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transport Factor 2 (NUTF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transport Factor 2 (NUTF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transport Factor 2 (NUTF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transport Factor 2 (NUTF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transport Factor 2 (NUTF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transport Factor 2 (NUTF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transport Factor 2 (NUTF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transport Factor 2 (NUTF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transport Factor 2 (NUTF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transport Factor 2 (NUTF2) ELISA Kit Customized Service Offer
  1. "Isolation of cDNA coding for the placental protein 15 (PP15)."Nucleic Acids Res. 16:4721-4721(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62."J. Cell Biol. 129:925-937(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]