Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1)

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CCS-3; CCS3; EEF-1; EEF1A; EF-Tu; EF1A; FLJ25721; GRAF-1EF; LENG7; PTI1; eEF1A-1; Leukocyte Receptor Cluster(LRC)Member 7; Elongation factor Tu

Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1)
Elongation factor 1-alpha 1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.EF1-alpha showed strong nuclear staining and diffuse cytoplasmic staining in human foreskin fibroblasts. In contrast, EF1-beta, -gamma, and -delta showed a perinuclear distribution and colocalized with an endoplasmic reticulum resident protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF020Hu01 Recombinant Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAF020Hu21 Monoclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) WB; IHC; ICC; IP.
PAF020Hu01 Polyclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) WB; IHC; ICC; IP.
Assay Kits SEF020Hu ELISA Kit for Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Eukaryotic Translation Elongation Factor 1 Alpha 1 (EEF1a1) ELISA Kit Customized Service Offer
  1. "The primary structure of the alpha subunit of human elongation factor 1. Structural aspects of guanine-nucleotide-binding sites."Eur. J. Biochem. 155:167-171(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha."J. Biol. Chem. 264:5791-5798(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Retropseudogenes constitute the major part of the human elongation factor 1 alpha gene family."Nucleic Acids Res. 18:1513-1516(1990) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Structure of the amino-terminal end of mammalian elongation factor Tu."Nucleic Acids Res. 14:2409-2409(1986) [PubMed] [Europe PMC] [Abstract]