Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR)

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Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR)
Nagasawa et al. (1997) isolated a cDNA for a novel human protein containing both a leucine-rich repeat (LRR) and an immunoglobulin (Ig)-like domain. ISLR was referred to as ISLR for 'immunoglobulin superfamily containing LRR.' The predicted protein comprises 428 amino acids and contains a hydrophobic N-terminal 18-amino acid putative signal peptide. Despite the variety of their functions, all members of the Ig superfamily are involved in adhesion or binding to other proteins in solution or at the cell surface. Therefore it is possible that the ISLR protein may also interact with other proteins or cells. On Northern blot analysis, the authors found a 2.4-kb ISLR transcript in various human tissues, including retina, heart, skeletal muscle, prostate, ovary, small intestine, thyroid, adrenal cortex, testis, stomach, and spinal cord, as well as fetal lung and fetal kidney.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH781Hu01 Recombinant Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAH781Hu21 Monoclonal Antibody to Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) WB; IHC; ICC; IP.
PAH781Hu01 Polyclonal Antibody to Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) WB; IHC; ICC; IP.
Assay Kits SEH781Hu ELISA Kit for Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Immunoglobulin Superfamily Containing Leucine Rich Repeat Protein (ISLR) ELISA Kit Customized Service Offer
  1. "Cloning of the cDNA for a new member of the immunoglobulin superfamily (ISLR) containing leucine-rich repeat (LRR)."Genomics 44:273-279(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Human and mouse ISLR (immunoglobulin superfamily containing leucine-rich repeat) genes: genomic structure and tissue expression."Genomics 61:37-43(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]