The Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1, which is a polypeptide protein hormone similar in molecular structure to insulin. IGF-1 plays an important role in growth and continues to have anabolic effects in adults - meaning that it can induce hypertrophy of skeletal muscle and other target tissues. Mice lacking the IGF-1 receptor die late in development, and show a dramatic reduction in body mass, testifying to the strong growth-promoting effect of this receptor. Mice carrying only one functional copy of igf1r are normal, but exhibit a ~15% decrease in body mass.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB659Hu01 | Recombinant Insulin Like Growth Factor 1 Receptor (IGF1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB659Hu01 | Polyclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. |
MAB659Hu22 | Monoclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. | |
MAB659Hu21 | Monoclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. | |
Assay Kits | SEB659Hu | ELISA Kit for Insulin Like Growth Factor 1 Receptor (IGF1R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB659Mu01 | Recombinant Insulin Like Growth Factor 1 Receptor (IGF1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB659Mu02 | Recombinant Insulin Like Growth Factor 1 Receptor (IGF1R) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB659Mu01 | Polyclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. |
PAB659Mu02 | Polyclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. | |
Assay Kits | SEB659Mu | ELISA Kit for Insulin Like Growth Factor 1 Receptor (IGF1R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB659Ra01 | Recombinant Insulin Like Growth Factor 1 Receptor (IGF1R) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB659Ra01 | Polyclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. |
MAB659Ra21 | Monoclonal Antibody to Insulin Like Growth Factor 1 Receptor (IGF1R) | WB; IHC; ICC; IP. | |
Assay Kits | SEB659Ra | ELISA Kit for Insulin Like Growth Factor 1 Receptor (IGF1R) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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