Biotin-Linked Polyclonal Antibody to Cyclic Adenosine Monophosphate (cAMP)

c-AMP; 3'-5'-Cyclic Adenosine Monophosphate; Adenosine Cyclophosphate


The antibody is a rabbit polyclonal antibody raised against cAMP. It has been selected for its ability to recognize cAMP in immunohistochemical staining and western blotting.


Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.


Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.


The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.



Magazine Citations
Int J Clin Exp Pathol Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway PubMed: 26617802
Experimental Dermatology Light Emitting Diodes Down‐reCavia (Guinea pig )lates Cathelicidin, Kallikrein, and Toll‐like Receptor 2 Expressions in Keratinocytes and Rosacea‐like Mouse Skin Pubmed:27315464
arteriosclerosis thrombosis and vascular biology P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis. pubmed:28062501
Taylor & Francis Influences of Hyriopsis cumingii polysaccharides on mice immunosignaling molecules and T lymphocyte differentiation 09540105.2017.1306494
international journal of biological macromolecules Immunomodulatory effect of APS and PSP is mediated by Ca2+-cAMP and TLR4/NF-κB signaling pathway in macrophage. pubmed:27732877
Front Pharmacol.  Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. pubmed:28261091
Allergologia et immunopathologia The relation of innate and adaptive immunity with viral-induced acute asthma attacks: Focusing on IP-10 and cathelicidin pubmed:27955890
Journal of Enzyme Inhibition and Medicinal Chemistry Structural re-positioning, molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators … Pubmed:29768061
Frontiers in Physiology Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice Pubmed:29410630
Nanoscience and Nanotechnology Letters Dobutamine Up-Regulates Aquaporin 5 Expression in Septic Pulmonary Edema Model In Vitro via cAMP-PKA/CREB Signaling Pathway 10.1166:nnl.2018.2602
PLoS One Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides Pubmed:29394269
Theriogenology Developmental competence of buffalo (Bubalus bubalis) denuded oocytes cocultured with cumulus cells: Protective role of cumulus cells Pubmed:30092373
Evidence-Based Complementary and Alternative Medicine iTRAQ-Based Proteomics to Reveal the Mechanism of Hypothalamus in Kidney-Yin Deficiency Rats Induced by Levothyroxine
EXPERIMENTAL BIOLOGY AND MEDICINE Calcimimetic R568 improved cardiac remodeling by classic and novel renin-angiotensin system in spontaneously hypertensive rats Pubmed: 31159562
Scientific Reports Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion Pubmed: 31863073
REPRODUCTION FERTILITY AND DEVELOPMENT Cytoplasm lipids can be modulated through hormone-sensitive lipase and are related to mitochondrial function in porcine IVM oocytes Pubmed: 32172783
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY Astragaloside IV relieves gestational diabetes mellitus in genetic mice through reducing hepatic gluconeogenesis Pubmed: 32160476
J Physiol Biochem Altered absorptive function in the gall bladder during cholesterol gallstone formation is associated with abnormal NHE3 complex formation Pubmed: 32557227
Biomed Pharmacother Antihypertensive effects of allicin on spontaneously hypertensive rats via vasorelaxation and hydrogen sulfide mechanisms Pubmed: 32480217
Legal Medicine DNA microarray analysis of hypothermia-exposed murine lungs for identification of forensic biomarkers Pubmed: 33161360
Neuropeptides Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway 33253929
Oxidative Medicine and Cellular Longevity A Green and Blue Monochromatic Light Combination Therapy Reduces Oxidative Stress and Enhances B-Lymphocyte Proliferation through Promoting ¡­ 33828639
Physiological crosstalk between the Mel1a and Mel1c pathways modulates melatonin-mediated, monochromatic light combination-induced bursa B-lymphocyte?¡­
Pflügers Archiv : European journal of physiology The role of adrenergic and muscarinic receptors in stress-induced cardiac injury 34245378
Theranostics Sult2b1 deficiency exacerbates ischemic stroke by promoting pro-inflammatory macrophage polarization in mice 34815805
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