On July 7, 2020, professor Kenta Maruyama from Osaka University WPI Immunology Frontier Research Center published a paper on Cell. The paper titled RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis.The ELISA kit (CTX1, CEA665Mu) of Cloud-Clone brand was chosed to determine the concentation of PVR in this article, we are so proud for supporting the reaserchers.Gastrointestinal enterochromaffin cells regulate bone and gut homeostasis via serotonin (5-hydroxytryptamine [5-HT]) production. A recent report suggested that gut microbes regulate 5-HT levels; however, the precise underlying molecular mechanisms are unexplored. Here, we reveal that the cation channel Pie......2020-09-24

On July 9, 2020, professor Minjia Tan from Shanghai institute of materia medica of Chinese academy of sciences, professor Ting Xiao from Chinese academy of medical sciences and Peking union medical college, professor Fuchu He and Yi Wang from Beijing institute of lifeomics and professor Jing Li from Shanghai Jiao Tong university co-authored published a paper on Cell. The paper titled Integrative Proteomic Characterization of Human Lung Adenocarcinoma.The ELISA kit (HSP90aB1, SED522Hu) of Cloud-Clone brand was chosed to determine the concentation of PVR in this article, we are so proud for supporting the reaserchers.Genomic studies of lung adenocarcinoma (LUAD) have advanced our under......2020-09-22

On June 8, 2020, professor Carlos Fernández de Larrea from xospital Clínic de Barcelona published a paper titled Nectin-2 Expression on malignant plasma cells is associated with better response to TIGIT blockade in multiple myeloma on Clinical cancer research.The ELISA kit (PVR, SEB550Hu) of Cloud-Clone brand was chosed to determine the concentation of PVR in this article, we are so proud for supporting the reaserchers.T-cell immunoreceptor with Ig and ITIM domain (TIGIT) blockade could represent an alternative therapeutic option to release the immune response in patients with multiple myeloma. Here we analyzed the expression of TIGIT and its ligands poliovirus receptor (PVR) and......2020-09-22

On May 28, 2020, professor Aiping Lu from Southern Medical University and Ge Zhang from Hong Kong Baptist University co-authored with Bao-Ting Zhang from the Chinese University of Hong Kong published a paper titled A Loop-Based and AGO-Incorporated Virtual Screening Model Targeting AGO-Mediated miRNA-mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice on Advanced science.The ELISA kit (CTX1, CEA665Mu) of Cloud-Clone brand was chosed to determine the concentation of CTX1 in this article, we are so proud for supporting the reaserchers.Several virtual screening models are proposed to screen small molecules only targeting primary miRNAs without selec......2020-09-22

On June 16, 2020, professorZhongzhou Yang from model animal research centerof Nanjing university co-authored with Wengong Wang from Peking university health science centerpublished apaper titledHepatic HuR modulates lipid homeostasis in response to high-fat dietonNature communications.The ELISA kit (APOE, SEA704Mu; APOB, SEC003Mu) of Cloud-Clone brand was chosed to determine the concentation of APOE and APOBin this article, we are so proud for supporting the reaserchers.Lipid transport and ATP synthesis are critical for the progression of non-alcoholic fatty liver disease (NAFLD), but the underlying mechanisms are largely unknown. Here, we report that the RNA-binding protein HuR (ELAVL......2020-09-18

On June24, 2020, professorMutsuhiro Takekawa frominstitute of medical science of university of Tokyopublished apaper titledStress-responsive MTK1 SAPKKK serves as a redox sensor that mediates delayed and sustainedactivation of SAPKs by oxidative stressonScience Advances.The polyclonalantibody(GADD45b,PAL535Hu01) ofCloud-Clone brand was chosed to conduct immunoprecipitationin this article, we are so proud for supporting the reaserchers.Cells respond to oxidative stress by inducing intracellular signaling, including stress-activated p38 and JNK MAPK (SAPK) pathways, but the underlying mechanisms remain unclear. Here, we report that the MAP three kinase 1 (MTK1) SAPK kinase kinase (SAPKKK......2020-09-18