Interleukin 15 (IL15)

Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukin 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Hu01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
APA061Hu01 Active Interleukin 15 (IL15) Cell culture; Activity Assays.
Antibodies PAA061Hu01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
MAA061Hu22 Monoclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
LAA061Hu71 Biotin-Linked Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC.
MAA061Hu21 Monoclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits SEA061Hu ELISA Kit for Interleukin 15 (IL15) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Mu01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
RPA061Mu02 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Mu01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
LAA061Mu71 Biotin-Linked Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC.
LAA061Mu81 FITC-Linked Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IF.
PAA061Mu02 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits SEA061Mu ELISA Kit for Interleukin 15 (IL15) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Ra01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Ra01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
MAA061Ra21 Monoclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
LAA061Ra72 Biotin-Linked Monoclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC.
Assay Kits SEA061Ra ELISA Kit for Interleukin 15 (IL15) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Gu01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Gu01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 15 (IL15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 15 (IL15) ELISA Kit Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Rb01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Rb52 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
PAA061Rb51 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 15 (IL15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 15 (IL15) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Po01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Po01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 15 (IL15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 15 (IL15) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Bo01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Bo01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
MAA061Bo21 Monoclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
LAA061Bo81 FITC-Linked Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IF.
Assay Kits SEA061Bo ELISA Kit for Interleukin 15 (IL15) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Cp01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Cp01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 15 (IL15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 15 (IL15) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Ga01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Ga01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits SEA061Ga ELISA Kit for Interleukin 15 (IL15) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA061Fi01 Recombinant Interleukin 15 (IL15) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA061Fi01 Polyclonal Antibody to Interleukin 15 (IL15) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 15 (IL15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 15 (IL15) ELISA Kit Customized Service Offer
  1. "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor."Science 264:965-968(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic sequence and chromosomal location of the human interleukin-15 gene (IL15)."Cytokine 8:667-674(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of a novel interleukin-15 (IL-15) transcript isoform generated by alternative splicing in human small cell lung cancer cell lines."Oncogene 12:2187-2192(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides."Proc. Natl. Acad. Sci. U.S.A. 94:14444-14449(1997) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Engineering a high-affinity anti-IL-15 antibody: crystal structure reveals an alpha-helix in VH CDR3 as key component of paratope."J. Mol. Biol. 406:160-175(2011) [PubMed] [Europe PMC] [Abstract]