Interleukin 17 (IL17)

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IL17A; CTLA8; IL-17A; Cytotoxic T-Lymphocyte-Associated Protein 8

Interleukin 17 (IL17)

Interleukin 17 (IL-17; also known as IL-17A) is a 30 - 35 kDa variably glycosylated homodimeric protein that belongs to a unique family of cysteine-knot related proteins. Its sequence was originally isolated from an activated rodent hybridoma and termed CTLA-8 . It is synthesized as a 155 amino acid (aa) precursor that contains a 23 aa signal sequence and a 15 kDa, 132 aa mature segment. Although there are two intrachain disulfide bonds that create a ring reminiscent of those found in cysteine-knot proteins, the actual closed knot structure does not appear to form. IL-17 has one potential N-linked glycosylation site.IL-17, a T cell-derived proinf lammatory cytokine, is produced by TCRα/β+CD4-CD8- thymocytes, as well as by activated CD4+ and CD4+CD45RO+ memory T cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Hu01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
EPA063Hu61 Eukaryotic Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
APA063Hu01 Active Interleukin 17 (IL17) Cell culture; Activity Assays.
Antibodies PAA063Hu01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Hu22 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
PAA063Hu06 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Hu21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Hu ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA063Hu CLIA Kit for Interleukin 17 (IL17) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Mu01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
RPA063Mu02 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Mu01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
PAA063Mu02 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Mu22 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Mu ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA063Mu CLIA Kit for Interleukin 17 (IL17) Chemiluminescent immunoassay for Antigen Detection.
HEA063Mu High Sensitive ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Ra01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Ra01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Ra21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Ra ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Rb01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Rb51 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
LAA063Rb71 Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC.
MAA063Rb21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Rb ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Ca01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Ca01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Ca21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Ca ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Po01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Po01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Po21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Po ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Bo01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Bo01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Bo21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Bo ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Ov01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Ov01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Ov21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Ov ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Eq01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Eq01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
MAA063Eq21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits SEA063Eq ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA063Ga01 Recombinant Interleukin 17 (IL17) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA063Ga01 Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
LAA063Ga81 FITC-Linked Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IF.
LAA063Ga71 Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC.
MAA063Ga21 Monoclonal Antibody to Interleukin 17 (IL17) WB; IHC; ICC; IP.
Assay Kits CEA063Ga ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.
SEA063Ga ELISA Kit for Interleukin 17 (IL17) Enzyme-linked immunosorbent assay for Antigen Detection.
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  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
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  5. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Structure of IL-17A in complex with a potent, fully human neutralizing antibody." J. Mol. Biol. 394:905-921(2009) [PubMed] [Europe PMC] [Abstract]