Leptin (LEP)

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OB; OBS; Obesity Homolog; Obesity Factor; Obese Protein

Leptin (LEP)

Leptin is a protein hormone with important effects in regulating body weight, metabolism and reproductive function. Leptin is a 16-kD protein that plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. Leptin acts through the leptin receptor (LEPR), a single-transmembrane-domain receptor of the cytokine receptor family, which is found in many tissues in several alternatively spliced forms. The LEP gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Hu01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
APA084Hu01 Active Leptin (LEP) Cell culture; Activity Assays.
Antibodies LAA084Hu71 Biotin-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC.
LAA084Hu81 FITC-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IF.
PAA084Hu01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Hu21 Monoclonal Antibody to Leptin (LEP) WB
MAA084Hu22 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Hu23 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Hu24 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Hu25 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Hu ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA084Hu CLIA Kit for Leptin (LEP) Chemiluminescent immunoassay for Antigen Detection.
HEA084Hu High Sensitive ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Mu01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Mu02 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Mu03 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
APA084Mu01 Active Leptin (LEP) Cell culture; Activity Assays.
Antibodies PAA084Mu01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
LAA084Mu71 Biotin-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC.
LAA084Mu81 FITC-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IF.
PAA084Mu02 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Mu21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Mu ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA084Mu CLIA Kit for Leptin (LEP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Ra01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Ra01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
LAA084Ra71 Biotin-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC.
MAA084Ra21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Ra ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA084Ra CLIA Kit for Leptin (LEP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Rb01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Rb51 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Rb21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Rb ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Si01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Leptin (LEP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leptin (LEP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leptin (LEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leptin (LEP) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Ca01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Ca01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Ca21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Ca ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Po01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Po02 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Po03 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Po04 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Po01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Po21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Po ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA084Po CLIA Kit for Leptin (LEP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Bo01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Bo01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Bo21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
LAA084Bo71 Biotin-Linked Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC.
Assay Kits SEA084Bo ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Cp01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Cp01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Leptin (LEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leptin (LEP) ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Ov01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Ov01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Ov ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Eq01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA084Eq02 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Eq01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Eq21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
PAA084Eq02 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Eq ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA084Ga01 Recombinant Leptin (LEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA084Ga01 Polyclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
MAA084Ga21 Monoclonal Antibody to Leptin (LEP) WB; IHC; ICC; IP.
Assay Kits SEA084Ga ELISA Kit for Leptin (LEP) Enzyme-linked immunosorbent assay for Antigen Detection.
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  2. ErratumNature 374:479-479(1995)
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  9. ErratumJ. Biol. Chem. 274:28058-28058(1999)
  10. "Leptin is a four-helix bundle: secondary structure by NMR."FEBS Lett. 407:239-242(1997) [PubMed] [Europe PMC] [Abstract]
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  12. "A novel polymorphism in the leptin gene."Hum. Mutat. 12:220-220(1998)
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