Colony Stimulating Factor 1, Macrophage (MCSF)

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CSF1; M-CSF; Lanimostim; Processed macrophage colony-stimulating factor 1

Colony Stimulating Factor 1, Macrophage (MCSF)

Colony-stimulating factors (CSFs) are secreted glycoproteins which bind to receptor proteins on the surfaces of hemopoietic stem cells and thereby activate intracellular signaling pathways which can cause the cells to proliferate and differentiate into a specific kind of blood cell. The substance which was found to stimulate formation of colonies of macrophages, for instance, was called macrophage colony-stimulating factor, and so on.

Macrophage Colony-stimulating factor is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types.The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA090Hu01 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
APA090Hu01 Active Colony Stimulating Factor 1, Macrophage (MCSF) Cell culture; Activity Assays.
RPA090Hu02 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA090Hu01 Polyclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
MAA090Hu22 Monoclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
Assay Kits SEA090Hu ELISA Kit for Colony Stimulating Factor 1, Macrophage (MCSF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA090Mu01 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
RPA090Mu02 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
APA090Mu01 Active Colony Stimulating Factor 1, Macrophage (MCSF) Cell culture; Activity Assays.
EPA090Mu61 Eukaryotic Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
RPA090Mu03 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
APA090Mu61 Active Colony Stimulating Factor 1, Macrophage (MCSF) Cell culture; Activity Assays.
Antibodies PAA090Mu01 Polyclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
PAA090Mu02 Polyclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
Assay Kits SEA090Mu ELISA Kit for Colony Stimulating Factor 1, Macrophage (MCSF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA090Ra01 Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA090Ra01 Polyclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
MAA090Ra21 Monoclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) WB; IHC; ICC; IP.
Assay Kits SEA090Ra ELISA Kit for Colony Stimulating Factor 1, Macrophage (MCSF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Colony Stimulating Factor 1, Macrophage (MCSF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Colony Stimulating Factor 1, Macrophage (MCSF) Polyclonal Antibody Customized Service Offer
Assay Kits SEA090Po ELISA Kit for Colony Stimulating Factor 1, Macrophage (MCSF) Enzyme-linked immunosorbent assay for Antigen Detection.
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  20. "Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor."Cancer Res. 69:9498-9506(2009) [PubMed] [Europe PMC] [Abstract]
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