Macrophage Derived Chemokine (MDC)

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CCL22; ABCD1; DC/B-CK; SCYA22; STCP1; Chemokine C-C-Motif Ligand 22; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 22; Stimulated T-Cell Chemotactic Protein 1

Macrophage Derived Chemokine (MDC)

CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.

The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA091Hu01 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
APA091Hu01 Active Macrophage Derived Chemokine (MDC) Cell culture; Activity Assays.
Antibodies PAA091Hu01 Polyclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
MAA091Hu22 Monoclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
MAA091Hu21 Monoclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
Assay Kits SEA091Hu ELISA Kit for Macrophage Derived Chemokine (MDC) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA091Hu CLIA Kit for Macrophage Derived Chemokine (MDC) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA091Mu01 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
RPA091Mu02 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA091Mu01 Polyclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
PAA091Mu02 Polyclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
Assay Kits SEA091Mu ELISA Kit for Macrophage Derived Chemokine (MDC) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA091Mu CLIA Kit for Macrophage Derived Chemokine (MDC) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA091Ra01 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA091Ra01 Polyclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
MAA091Ra21 Monoclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
Assay Kits SEA091Ra ELISA Kit for Macrophage Derived Chemokine (MDC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA091Po01 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Macrophage Derived Chemokine (MDC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Macrophage Derived Chemokine (MDC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Macrophage Derived Chemokine (MDC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Macrophage Derived Chemokine (MDC) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA091Bo01 Recombinant Macrophage Derived Chemokine (MDC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA091Bo01 Polyclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
MAA091Bo21 Monoclonal Antibody to Macrophage Derived Chemokine (MDC) WB; IHC; ICC; IP.
Assay Kits SEA091Bo ELISA Kit for Macrophage Derived Chemokine (MDC) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes."J. Biol. Chem. 272:25229-25237(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells."J. Exp. Med. 185:1595-1604(1997) [PubMed] [Europe PMC] [Abstract]
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