Matrix Metalloproteinase 3 (MMP3)
[Edit]SL1; STMY; STMY1; STR1; Progelatinase; Stromelysin 1; Transin-1
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MMP-3 is secreted from the cells as a proenzyme. The proenzyme has been shown to stimulate plasminogen activation. The N-terminal pro-domain contains the cysteine switch motif conserved in MMPs that maintains MMP-3 in the latent state. Activation of the proenzyme results in the removal of the pro-domain. MMP-3 activation can be achieved in vitro by proteases such as itself, chyrotrypsin, neutrophil elastase and plasma kallikrein, and by mercury compounds.
The resulting active enzyme consists of a catalytic domain with a zinc-binding motif conserved in metzincins. A short hinge peptide links the catalytic domain to the C-terminal hemopexin-like domain. The active MMP-3 is capable of cleaving types III, IV, IX and X collagen, aggrecan, fibronectin, laminin, IGFBP-3, serpins, and IL-1 .
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Mu01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA101Mu02 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA101Mu01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| PAA101Mu02 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Mu | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Mu | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Rb01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA101Rb51 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| MAA101Rb21 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Rb | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Rb | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Ca01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA101Ca01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| MAA101Ca21 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Ca | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Ca | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Po01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA101Po01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| MAA101Po21 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Po | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Po | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Bo01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA101Bo01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| MAA101Bo21 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Bo | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Bo | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Equus caballus; Equine (Horse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA101Eq01 | Recombinant Matrix Metalloproteinase 3 (MMP3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA101Eq01 | Polyclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. |
| MAA101Eq21 | Monoclonal Antibody to Matrix Metalloproteinase 3 (MMP3) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA101Eq | ELISA Kit for Matrix Metalloproteinase 3 (MMP3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA101Eq | CLIA Kit for Matrix Metalloproteinase 3 (MMP3) | Chemiluminescent immunoassay for Antigen Detection. |
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