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Nerve growth factor (NGF) is a naturally occurring molecule in the body which stimulates the growth and differentiation of the sympathetic and certain sensory nerves. NGF is a protein that consists of 3 types of polypeptide chains -- alpha, beta and gamma -- that interact to form the protein. The NGF beta chain (NGFB) is solely responsible for the nerve growth stimulating activity of NGF. The NGFB gene is in chromosome band 1p22. An ointment containing NGF has been reported to help heal bedsores (decubiti).This complex contains 2 identical 118-amino acid beta-chains, which are solely responsible for nerve growth stimulating activity of NGF. Human DNA fragments coding for NGF were identified by Zabel et al. (1984) using a mouse submaxillary cDNA probe.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Mu01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA105Mu02 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA105Mu01 | Active Nerve Growth Factor (NGF) | Cell culture; Activity Assays. | |
| RPA105Mu03 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA105Mu01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| PAA105Mu02 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Mu | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Ra01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA105Ra61 | Eukaryotic Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA105Ra01 | Active Nerve Growth Factor (NGF) | Cell culture; Activity Assays. | |
| Antibodies | PAA105Ra01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Ra21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| MAA105Ra22 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Ra | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA105Ra | CLIA Kit for Nerve Growth Factor (NGF) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Cavia (Guinea pig )
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Gu01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA105Gu01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Gu21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Gu | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Nerve Growth Factor (NGF) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Nerve Growth Factor (NGF) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Nerve Growth Factor (NGF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA105Rb | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rhesus monkey (Simian)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Si01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA105Si01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Si21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Si | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Po01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA105Po01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Po21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Po | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Bo01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA105Bo01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Bo21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Bo | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Ovis aries; Ovine (Sheep)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Nerve Growth Factor (NGF) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Nerve Growth Factor (NGF) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Nerve Growth Factor (NGF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEA105Ov | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Equus caballus; Equine (Horse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Eq01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Nerve Growth Factor (NGF) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Nerve Growth Factor (NGF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Nerve Growth Factor (NGF) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Nerve Growth Factor (NGF) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA105Ga01 | Recombinant Nerve Growth Factor (NGF) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA105Ga01 | Polyclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. |
| MAA105Ga21 | Monoclonal Antibody to Nerve Growth Factor (NGF) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA105Ga | ELISA Kit for Nerve Growth Factor (NGF) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Human beta-nerve growth factor gene sequence highly homologous to that of mouse."Nature 303:821-825(1983) [PubMed] [Europe PMC] [Abstract]
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- "Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI."J. Biol. Chem. 285:11793-11799(2010) [PubMed] [Europe PMC] [Abstract]
- "Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor."Nature 401:184-188(1999) [PubMed] [Europe PMC] [Abstract]
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- ErratumNat. Genet. 23:373-373(1999)
- "A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception."Hum. Mol. Genet. 13:799-805(2004) [PubMed] [Europe PMC] [Abstract]
- "A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy."J. Med. Genet. 48:131-135(2011) [PubMed] [Europe PMC] [Abstract]
- "Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort." J. Neurol. 259:1673-1685(2012) [PubMed] [Europe PMC] [Abstract]