Creatine Kinase, Muscle (CKM)

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CK-MM; CKMM; CK3; CK-M; MM-CK; M-CK; Creatine kinase M-type, N-terminally processed

Creatine Kinase, Muscle (CKM)

CKM is a cytoplasmic enzyme involved in cellular energy homeostasis. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine and between phospho-creatine and ADP. Its functional entity is a MM-CK homodimer in striated (sarcomeric) skeletal and cardiac muscle.In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Since no other organ than cardiac muscle expresses significant levels of MB-CK, this clinical test is still fairly reliable, together with troponin-T, for diagnosing a myocardial infarction.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Hu01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Hu01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
MAA109Hu22Monoclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
LAA109Hu71Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;WB;ELISA
Assay KitsSEA109HuELISA Kit for Creatine Kinase, Muscle (CKM)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Mu01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
RPA109Mu02Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Mu01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
LAA109Mu71Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;WB;ELISA
LAA109Mu81FITC-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;ICC;IF;WB
PAA109Mu02Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA109MuELISA Kit for Creatine Kinase, Muscle (CKM)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Ra01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
NPA109Ra01Native Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Ra01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
LAA109Ra71Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;WB;ELISA
MAA109Ra21Monoclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA109RaELISA Kit for Creatine Kinase, Muscle (CKM)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Rb01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Rb51Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
MAA109Rb21Monoclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA109RbELISA Kit for Creatine Kinase, Muscle (CKM)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Ca01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Ca01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Creatine Kinase, Muscle (CKM)CLIA Kit Customized Service Offer
n/aELISA Kit for Creatine Kinase, Muscle (CKM)ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Po01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Po01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
LAA109Po81FITC-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;ICC;IF;WB
LAA109Po71Biotin-Linked Polyclonal Antibody to Creatine Kinase, Muscle (CKM)IHC;WB;ELISA
Assay Kitsn/aCLIA Kit for Creatine Kinase, Muscle (CKM)CLIA Kit Customized Service Offer
n/aELISA Kit for Creatine Kinase, Muscle (CKM)ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Bo01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Bo01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Creatine Kinase, Muscle (CKM)CLIA Kit Customized Service Offer
n/aELISA Kit for Creatine Kinase, Muscle (CKM)ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Ga01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Ga01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Creatine Kinase, Muscle (CKM)CLIA Kit Customized Service Offer
n/aELISA Kit for Creatine Kinase, Muscle (CKM)ELISA Kit Customized Service Offer

Organism species: Danio rerio (Zebrafish)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA109Fi01Recombinant Creatine Kinase, Muscle (CKM)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA109Fi01Polyclonal Antibody to Creatine Kinase, Muscle (CKM)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Creatine Kinase, Muscle (CKM)CLIA Kit Customized Service Offer
n/aELISA Kit for Creatine Kinase, Muscle (CKM)ELISA Kit Customized Service Offer
  1. "Isolation and sequence analysis of a full-length cDNA for human M creatine kinase."Biochem. Biophys. Res. Commun. 140:981-989(1986) [PubMed] [Europe PMC] [Abstract]
  2. "Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene."J. Biol. Chem. 263:17142-17149(1988) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Muscle creatine kinase isoenzyme expression in adult human brain."J. Biol. Chem. 265:6403-6409(1990) [PubMed] [Europe PMC] [Abstract]
  6. "cDNA cloning and mapping of the human creatine kinase M gene to 19q13."Am. J. Hum. Genet. 40:115-125(1987) [PubMed] [Europe PMC] [Abstract]
  7. "Crystallization and preliminary X-ray analysis of human muscle creatine kinase."Acta Crystallogr. D 55:669-670(1999) [PubMed] [Europe PMC] [Abstract]