Galectin 8 (GAL8)
[Edit]LGALS8; PCTA1; Po66-CBP; Prostate Carcinoma Tumor Antigen 1; Lectin,Galactoside-Binding Soluble 8; Po66 carbohydrate-binding protein; Prostate carcinoma tumor antigen 1
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Galectin-8 is one of the galectins, beta-galactoside-binding lectins with conserved carbohydrate recognition domains (CRD). Galectin-8 essentially consists of two carbohydrate recognition domains separated by a linker that bears no similarity to any known protein. The gene symbol is LGALS8 [galactose-specific soluble lectin 8; lectin galactoside-binding soluble 8]. Galectin-8 has been identified originally as PCTA1 [Prostate carcinoma tumor antigen 1], an antigen expressed by prostate cancer cells .
Several isoforms appear to be expressed differentially in various tumoral cells . The protein is identical with Po66-CBP [Po66 carbohydrate-binding protein], identified by the Po66 monoclonal antibody.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA308Hu01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA308Hu01 | Active Galectin 8 (GAL8) | Cell culture; Activity Assays. | |
| Antibodies | PAA308Hu01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| MAA308Hu22 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| LAA308Hu71 | Biotin-Linked Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC. | |
| LAA308Hu81 | FITC-Linked Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IF. | |
| MAA308Hu21 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| MAA308Hu23 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| MAA308Hu24 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; ICC/IF | |
| MAA308Hu27 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| MAA308Hu25 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| MAA308Hu29 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA308Hu | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA308Mu01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA308Mu02 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA308Mu01 | Active Galectin 8 (GAL8) | Cell culture; Activity Assays. | |
| Antibodies | PAA308Mu01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| PAA308Mu02 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA308Mu | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA308Ra01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA308Ra01 | Active Galectin 8 (GAL8) | Cell culture; Activity Assays. | |
| Antibodies | PAA308Ra01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Galectin 8 (GAL8) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Galectin 8 (GAL8) | ELISA Kit Customized Service Offer |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA308Po01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA308Po01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Galectin 8 (GAL8) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Galectin 8 (GAL8) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA308Bo01 | Recombinant Galectin 8 (GAL8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA308Bo01 | Active Galectin 8 (GAL8) | Cell culture; Activity Assays. | |
| Antibodies | PAA308Bo01 | Polyclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. |
| MAA308Bo21 | Monoclonal Antibody to Galectin 8 (GAL8) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA308Bo | ELISA Kit for Galectin 8 (GAL8) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family."Proc. Natl. Acad. Sci. U.S.A. 93:7252-7257(1996) [PubMed] [Europe PMC] [Abstract]
- "Galectin-8: on the road from structure to function."Trends Glycosci. Glycotechnol. 9:103-112(1997)
- "Molecular characterization of prostate carcinoma tumor antigen-1, PCTA-1, a human galectin-8 related gene."Oncogene 19:4405-4416(2000) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of the C-terminal Gal-bind lectin protein from human galectin-8."Submitted (FEB-2008) to the PDB data bank
- "Crystal structure of N-terminal domain of human galectin-8."Submitted (MAY-2008) to the PDB data bank
- "Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans."J. Biol. Chem. 286:11346-11355(2011) [PubMed] [Europe PMC] [Abstract]