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Transcription Factor P65 (NFKB3)

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Nuclear factor NF-kappa-B p65 subunit; NFKBP65; RELA; p65; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3

Transcription Factor P65 (NFKB3)
CCC A616
HGNC 9955
MGI 103290
PubMed 16135789
RGD 727889
UniProt Q04206
Wiki RELA

The transcriptional coactivator CBP/p300 associates with through 2 sites, an N-terminal domain that interacts with the C-terminal region of unphosphorylated p65, and a second domain that only interacts with p65 phosphorylated on serine-276. Phosphorylation by PKA both weakens the interaction between the N- and C-terminal regions of p65 and creates an additional site for interaction with CBP/p300. Therefore, PKA regulates the transcriptional activity of NF-kappa-B by modulating its interaction with CBP/p300.

The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB ), which inactivate NFKB by trapping it in the cytoplasm.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA616Hu01 Recombinant Transcription Factor P65 (NFKB3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA616Hu01 Polyclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IP.
MAA616Hu22 Monoclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IP.
Assay Kits SEA616Hu ELISA Kit for Transcription Factor P65 (NFKB3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA616Mu01 Recombinant Transcription Factor P65 (NFKB3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA616Mu01 Polyclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IP.
LAA616Mu71 Biotin-Linked Polyclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC.
LAA616Mu81 FITC-Linked Polyclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IF.
Assay Kits n/a CLIA Kit for Transcription Factor P65 (NFKB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor P65 (NFKB3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA616Ra01 Recombinant Transcription Factor P65 (NFKB3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA616Ra01 Polyclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IP.
MAA616Ra21 Monoclonal Antibody to Transcription Factor P65 (NFKB3) WB; IHC; ICC; IP.
Assay Kits SEA616Ra ELISA Kit for Transcription Factor P65 (NFKB3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Danio rerio (Zebrafish)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA616Fi01 Recombinant Transcription Factor P65 (NFKB3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Transcription Factor P65 (NFKB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transcription Factor P65 (NFKB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transcription Factor P65 (NFKB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor P65 (NFKB3) ELISA Kit Customized Service Offer
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