Cyclin Dependent Kinase 5 (CDK5)


PSSALRE; CDKN5; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit;TPKII catalytic subunit

Cyclin Dependent Kinase 5 (CDK5)

Recently Cdk5 has emerged as an essential kinase in sensory pathways. Recent reports of Pareek et al. from NIH suggest its necessity in pain signaling. CDK5 is required for proper development of the brain and to be activated, CDK5 must associate with CDK5R1 or CDK5R2. Unlike other cyclin dependent kinases, CDK5 does not also require phosphorylation on the T loop so that binding with the activator is sufficient to activate the kinase. Cdk5 is involved in the processes of neuronal maturation and migration, phosphorylating the key intracellular adaptor of the reelin signaling chain.Experiments performed on mice lacking p35, a necessary activator of cdk5 in early brain development, showed that the normal layering of neurons was reversed in the cortex.

Organism species: Homo sapiens (Human)

ProteinsRPA739Hu01Recombinant Cyclin Dependent Kinase 5 (CDK5)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA739Hu01Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)WB, ICC, IHC-P, IHC-F, ELISA
LAA739Hu71Biotin-Linked Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)IHC;WB;ELISA
LAA739Hu81FITC-Linked Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)IHC;ICC;IF;WB
MAA739Hu21Monoclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
Assay KitsSEA739HuELISA Kit for Cyclin Dependent Kinase 5 (CDK5)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

Proteinsn/aRecombinant Cyclin Dependent Kinase 5 (CDK5)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)Polyclonal Antibody Customized Service Offer
Assay KitsSEA739MuELISA Kit for Cyclin Dependent Kinase 5 (CDK5)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

ProteinsRPA739Ra01Recombinant Cyclin Dependent Kinase 5 (CDK5)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA739Ra01Polyclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)WB, ICC, IHC-P, IHC-F, ELISA
MAA739Ra21Monoclonal Antibody to Cyclin Dependent Kinase 5 (CDK5)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA739RaELISA Kit for Cyclin Dependent Kinase 5 (CDK5)Enzyme-linked immunosorbent assay for Antigen Detection
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