Nitric Oxide Synthase 2, Inducible (NOS2)

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NOS2A; INOS; HEP-NOS; I-NOS; Hepatocytes Oxide Synthase; Peptidyl-cysteine S-nitrosylase NOS2

Nitric Oxide Synthase 2, Inducible (NOS2)

Nitric oxide synthase 2A (inducible, hepatocytes)is an enzyme encoded by the NOS2 gene. is produced by a group of enzymes called nitric oxide synthases (NOS). These enzymes catalyze the production of NO and L-citrulline from L-arginine, O2, and NADPH-derived electrons. Mammalian systems contain three well-characterized isoforms of the enzyme: neuronal NOS (nNOS, also called NOS1), inducible NOS (iNOS or NOS2), and endothelial NOS (eNOS or NOS3). The names reflect characteristics of the activity or the original tissues in which the enzymes were first described, but it is now known that each of these isoforms is expressed in a variety of tissues and cell types . The three main isoforms share structural similarities and have nearly identical catalytic mechanisms.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA837Hu01 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA837Hu02 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA837Hu01 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
MAA837Hu22 Monoclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
PAA837Hu02 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
LAA837Hu71 Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC.
Assay Kits SEA837Hu ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA837Hu High Sensitive ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA837Mu01 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA837Mu02 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA837Mu03 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
APA837Mu01 Active Nitric Oxide Synthase 2, Inducible (NOS2) Cell culture; Activity Assays.
Antibodies PAA837Mu01 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
PAA837Mu02 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
PAA837Mu03 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
LAA837Mu71 Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC.
Assay Kits SEA837Mu ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA837Ra01 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA837Ra02 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA837Ra01 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
MAA837Ra21 Monoclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
PAA837Ra02 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
Assay Kits SEA837Ra ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA837Rb01 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA837Rb51 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
MAA837Rb21 Monoclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
Assay Kits SEA837Rb ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA837Ca01 Recombinant Nitric Oxide Synthase 2, Inducible (NOS2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA837Ca01 Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
MAA837Ca21 Monoclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2) WB; IHC; ICC; IP.
Assay Kits SEA837Ca ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2) Enzyme-linked immunosorbent assay for Antigen Detection.
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  12. "Three members of the nitric oxide synthase II gene family (NOS2A, NOS2B, and NOS2C) colocalize to human chromosome 17."Genomics 27:526-530(1995) [PubMed] [Europe PMC] [Abstract]
  13. "Inducible nitric oxide synthase in the liver: regulation and function."Biochemistry (Mosc.) 63:766-781(1998) [PubMed] [Europe PMC] [Abstract]
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  15. "A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children."Lancet 360:1468-1475(2002) [PubMed] [Europe PMC] [Abstract]
  16. "Target-selective protein S-nitrosylation by sequence motif recognition."Cell 159:623-634(2014) [PubMed] [Europe PMC] [Abstract]
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  20. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  21. "Higher activity of the inducible nitric oxide synthase contributes to very early onset inflammatory bowel disease."Clin. Transl. Gastroenterol. 5:E46-E46(2014) [PubMed] [Europe PMC] [Abstract]