Chemokine C-C-Motif Receptor 5 (CCR5)


CD195; CC-CKR5; CCCKR5; CMKBR5; CHEMR13; HIV-1 fusion coreceptor

Chemokine C-C-Motif Receptor 5 (CCR5)

CCR5 is a member of the beta chemokine receptors family of integral membrane proteins.In Humans, the CCR5 gene location is on the short (p) arm at position 21 on chromosome 3. Certain populations have inherited the Delta 32 mutation resulting in the Genetic deletion of the CCR5 gene. Homozygous carriers of this mutation are resistant to HIV-1 infection. The CCR5 protein is a seven transmembrane protein which functions as a chemokine receptor in the CC chemokine group. The natural chemokine ligands that bind to this receptor are RANTES, MIP-1α and MIP-1β. CCR5 is predominantly expressed on T cells, macrophages, dendritic cells and microglia. It is likely that CCR5 plays a role in inflammatory responses to infection, though its exact role in normal immune function is unclear.

Organism species: Homo sapiens (Human)

ProteinsRPA906Hu01Recombinant Chemokine C-C-Motif Receptor 5 (CCR5)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA906Hu01Polyclonal Antibody to Chemokine C-C-Motif Receptor 5 (CCR5)WB, ICC, IHC-P, IHC-F, ELISA
MAA906Hu21Monoclonal Antibody to Chemokine C-C-Motif Receptor 5 (CCR5)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA906HuELISA Kit for Chemokine C-C-Motif Receptor 5 (CCR5)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

ProteinsRPA906Mu01Recombinant Chemokine C-C-Motif Receptor 5 (CCR5)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA906Mu01Polyclonal Antibody to Chemokine C-C-Motif Receptor 5 (CCR5)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Chemokine C-C-Motif Receptor 5 (CCR5)CLIA Kit Customized Service Offer
n/aELISA Kit for Chemokine C-C-Motif Receptor 5 (CCR5)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

ProteinsRPA906Ra01Recombinant Chemokine C-C-Motif Receptor 5 (CCR5)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA906Ra01Polyclonal Antibody to Chemokine C-C-Motif Receptor 5 (CCR5)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Chemokine C-C-Motif Receptor 5 (CCR5)CLIA Kit Customized Service Offer
n/aELISA Kit for Chemokine C-C-Motif Receptor 5 (CCR5)ELISA Kit Customized Service Offer
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  28. "CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum."Traffic 15:383-400(2014) [PubMed] [Europe PMC] [Abstract]