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Tumor Protein p53 (P53)

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TP53; LFS1; TRP53; Li-Fraumeni Syndrome; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Tumor Protein p53 (P53)
CCC A928
HGNC 11998
MGI 98834
PubMed 17311302
RGD 3889
UniProt P04637
Wiki TP53

The p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Hu01 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
APA928Hu01 Active Tumor Protein p53 (P53) Cell culture; Activity Assays.
RPA928Hu02 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
RPA928Hu03 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA928Hu01 Polyclonal Antibody to Tumor Protein p53 (P53) WB,ICC/IF
MAA928Hu22 Monoclonal Antibody to Tumor Protein p53 (P53) WB
LAA928Hu71 Biotin-Linked Polyclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC.
MAA928Hu21 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
MAA928Hu23 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
PAA928Hu02 Polyclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
MAA928Hu24 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
MAA928Hu25 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
MAA928Hu27 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
Assay Kits SEA928Hu ELISA Kit for Tumor Protein p53 (P53) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA928Hu CLIA Kit for Tumor Protein p53 (P53) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Mu01 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
RPA928Mu02 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA928Mu01 Polyclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
PAA928Mu02 Polyclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
Assay Kits SEA928Mu ELISA Kit for Tumor Protein p53 (P53) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA928Ra01 Recombinant Tumor Protein p53 (P53) Positive Control; Immunogen; SDS-PAGE; WB.
APA928Ra01 Active Tumor Protein p53 (P53) Cell culture; Activity Assays.
Antibodies PAA928Ra01 Polyclonal Antibody to Tumor Protein p53 (P53) WB,ICC/IF
MAA928Ra21 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
MAA928Ra22 Monoclonal Antibody to Tumor Protein p53 (P53) WB; IHC; ICC; IP.
Assay Kits SEA928Ra ELISA Kit for Tumor Protein p53 (P53) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Protein p53 (P53) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Protein p53 (P53) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Protein p53 (P53) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Protein p53 (P53) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Protein p53 (P53) ELISA Kit Customized Service Offer
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