Tumor Protein p53 (TP53)


p53; LFS1; TRP53; Li-Fraumeni Syndrome; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Tumor Protein p53 (TP53)

The p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity.

Organism species: Homo sapiens (Human)

ProteinsRPA928Hu01Recombinant Tumor Protein p53 (TP53)SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.
AntibodiesPAA928Hu01Polyclonal Antibody to Tumor Protein p53 (TP53)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
MAA928Hu22Monoclonal Antibody to Tumor Protein p53 (TP53)WB, ICC, IHC-P, IHC-F, ELISA
LAA928Hu71Biotin-Linked Polyclonal Antibody to Tumor Protein p53 (TP53)IHC;WB;ELISA
Assay KitsSEA928HuELISA Kit for Tumor Protein p53 (TP53)Enzyme-linked immunosorbent assay for Antigen Detection
SCA928HuCLIA Kit for Tumor Protein p53 (TP53)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

ProteinsRPA928Mu01Recombinant Tumor Protein p53 (TP53)SDS-PAGE; WB; ELISA; IP.
RPA928Mu02Recombinant Tumor Protein p53 (TP53)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA928Mu01Polyclonal Antibody to Tumor Protein p53 (TP53)WB, ICC, IHC-P, IHC-F, ELISA
PAA928Mu02Polyclonal Antibody to Tumor Protein p53 (TP53)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA928MuELISA Kit for Tumor Protein p53 (TP53)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

ProteinsRPA928Ra01Recombinant Tumor Protein p53 (TP53)SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.
AntibodiesPAA928Ra01Polyclonal Antibody to Tumor Protein p53 (TP53)WB, ICC, IHC-P, IHC-F, ELISA
MAA928Ra21Monoclonal Antibody to Tumor Protein p53 (TP53)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA928RaELISA Kit for Tumor Protein p53 (TP53)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

Proteinsn/aRecombinant Tumor Protein p53 (TP53)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Tumor Protein p53 (TP53)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Tumor Protein p53 (TP53)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Tumor Protein p53 (TP53)CLIA Kit Customized Service Offer
n/aELISA Kit for Tumor Protein p53 (TP53)ELISA Kit Customized Service Offer
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