Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant.The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester.
Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls. Once surfactant is secreted by the type II cells, it must be spread over the remaining type I cellular surface area. Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. The major surfactant deficiency in premature infants relates to the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids.
Organism species: Pan-species (General)
|CATALOG NO.||PRODUCT NAME||APPLICATIONS|
|Proteins||n/a||Complete Antigen of Phosphatidylglycerol (PG)||Antigenic Transformation Customized Service Offer|
|Antibodies||n/a||Monoclonal Antibody to Phosphatidylglycerol (PG)||Monoclonal Antibody Customized Service Offer|
|n/a||Polyclonal Antibody to Phosphatidylglycerol (PG)||Polyclonal Antibody Customized Service Offer|
|Assay Kits||n/a||CLIA Kit for Phosphatidylglycerol (PG)||CLIA Kit Customized Service Offer|
|n/a||ELISA Kit for Phosphatidylglycerol (PG)||ELISA Kit Customized Service Offer|