Phosphatidylglycerol (PG)

Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant.The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester.

Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls. Once surfactant is secreted by the type II cells, it must be spread over the remaining type I cellular surface area. Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. The major surfactant deficiency in premature infants relates to the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids.

Organism species: Pan-species (General)

Proteins n/a Complete Antigen of Phosphatidylglycerol (PG) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphatidylglycerol (PG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphatidylglycerol (PG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphatidylglycerol (PG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphatidylglycerol (PG) ELISA Kit Customized Service Offer