Amyloid Precursor Protein (APP)


AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein

Amyloid Precursor Protein (APP)

Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation and neural plasticity. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.Several alternative splicing isoforms of APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the neuronal ratio of these isoforms have been associated with Alzheimer's disease.

Organism species: Homo sapiens (Human)

ProteinsRPB020Hu01Recombinant Amyloid Precursor Protein (APP)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAB020Hu01Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
MAB020Hu22Monoclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
Assay KitsSEB020HuELISA Kit for Amyloid Precursor Protein (APP)Enzyme-linked immunosorbent assay for Antigen Detection.
SCB020HuCLIA Kit for Amyloid Precursor Protein (APP)Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

ProteinsRPB020Mu01Recombinant Amyloid Precursor Protein (APP)Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Mu02Recombinant Amyloid Precursor Protein (APP)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAB020Mu01Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
PAB020Mu02Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
LAB020Mu71Biotin-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC.
LAB020Mu81FITC-Linked Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IF.
Assay KitsSEB020MuELISA Kit for Amyloid Precursor Protein (APP)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

ProteinsRPB020Ra01Recombinant Amyloid Precursor Protein (APP)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAB020Ra01Polyclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
MAB020Ra21Monoclonal Antibody to Amyloid Precursor Protein (APP)WB; IHC; ICC; IP.
Assay KitsSEB020RaELISA Kit for Amyloid Precursor Protein (APP)Enzyme-linked immunosorbent assay for Antigen Detection.
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