Protein Tyrosine Phosphatase Receptor Type C (CD45)

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PTPRC; PTPR-C; LCA; B220; GP180; LY5; T200; Leukocyte common antigen

Protein Tyrosine Phosphatase Receptor Type C (CD45)

PTPRC is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP.

PTPRC is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB030Hu01 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
RPB030Hu02 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
EPB030Hu61 Eukaryotic Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
RPB030Hu03 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
APB030Hu61 Active Protein Tyrosine Phosphatase Receptor Type C (CD45) Cell culture; Activity Assays.
Antibodies PAB030Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
PAB030Hu02 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
MAB030Hu22 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
LAB030Hu71 Biotin-Linked Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC.
MAB030Hu21 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
MAB030Hu23 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
MAB030Hu24 Monoclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type C (CD45) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type C (CD45) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB030Mu01 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
RPB030Mu02 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB030Mu01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
PAB030Mu02 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
LAB030Mu71 Biotin-Linked Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC.
Assay Kits SEB030Mu ELISA Kit for Protein Tyrosine Phosphatase Receptor Type C (CD45) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB030Ra01 Recombinant Protein Tyrosine Phosphatase Receptor Type C (CD45) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB030Ra01 Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type C (CD45) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase Receptor Type C (CD45) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase Receptor Type C (CD45) ELISA Kit Customized Service Offer
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  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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  19. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]